ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023
Biomarkers for dementia in Latin American countries: Gaps and opportunities.
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Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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41citing papers in PubMed, 2 pooled it
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of apolipoprotein E variants on Alzheimer's disease in Latin America: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Pooled it
- Systematic review: fluid biomarkers and machine learning methods to improve the diagnosis from mild cognitive impairment to Alzheimer's disease.Alzheimer's research & therapy · 2023Pooled it
- Generalizability of EEG-Based DEMENTIA Classifiers: A Multicenter study of Alzheimer's, MCI, and FTD.medRxiv : the preprint server for health sciences · 2026Article
- Emerging directions in tauopathy research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Activities of daily living and their neural correlates across the Alzheimer's disease continuum: Evidence from a Latin American cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Contextualizing Blood-Based Biomarkers for Dementia Globally.Journal of neurochemistry · 2026Review
- The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Plasma ATN biomarkers across the alzheimer's disease continuum in a Chilean community- and clinic-based cohort.Alzheimer's research & therapy · 2026Article
- Towards a Latin American neuropsychiatry: challenges and opportunities.Lancet regional health. Americas · 2026Review
- Blood-based AT(N) biomarkers for Alzheimer's disease and frontotemporal lobar degeneration in Latin America.Nature aging · 2026Article
- The modified Rowland Universal Dementia Assessment Scale for dementia screening in the Peruvian population.Dementia & neuropsychologia · 2026Article
- Clinical Characterization of Probable Dementia with Lewy Bodies Based on the Initial Clinical Presentation in a Latin American Low- and Middle-Income Country.Neuro-degenerative diseases · 2026Article
- Computational whole-body-exposome models for global precision brain health.Nature communications · 2025Article
- Social exposome and brain health outcomes of dementia across Latin America.Nature communications · 2025Article
- Disease-Modifying Drugs for Alzheimer's Disease: Bending the Curve.Annals of Indian Academy of Neurology · 2025Article
- Dementia research in low-income and middle-income countries - a view from Latin America.Nature reviews. Neurology · 2025Review
- The silent saboteur: oxidative stress and the path to cognitive dysfunction.Neurodegenerative disease management · 2025Review
- P-tau217 as a Biomarker in Alzheimer's Disease: Applications in Latin American Populations.International journal of molecular sciences · 2025Review
- Global multi-specialty clinician perspectives on the implementation of Alzheimer's disease blood biomarkers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools.Behavioral sciences (Basel, Switzerland) · 2025Review
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Authors and funding
56 authors.
Mario A ParraSchool, of Psychological Sciences and Health, University of Strathclyde, Glasgow, UK.
Paulina OrellanaLatin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.
Tomas LeonGlobal Brain Health Institute, Trinity College, Dublin, Ireland.
Cabello G VictoriaLatin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.
Fernando HenriquezNeuropsychology and Clinical Neuroscience Laboratory (LANNEC), Physiopathology Department - Institute of Biomedical Sciences (ICBM), Neuroscience and East Neuroscience Departments, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Rodrigo GomezMemory and Neuropsychiatric Clinic (CMYN) Neurology Department, Hospital del Salvador y Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Constanza AvalosLatin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.
Andres DamianCentro Uruguayo de Imagenología Molecular (CUDIM) - Centro de Medicina Nuclear e Imagenología Molecular, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
Andrea SlachevskyMemory and Neuropsychiatric Clinic (CMYN) Neurology Department, Hospital del Salvador y Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Agustin IbañezLatin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Betty M TijmsAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, the Netherlands.
Jennifer S YokoyamaGlobal Brain Health Institute and the Memory and Aging Center, Weill Institute for Neurosciences, Departments of Neurology and Radiology & Biomedical Imaging, University of California, San Francisco (UCSF), San Francisco, California, USA.
Stefanie D Piña-EscuderoAtlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI), University of California San Francisco, San Francisco, California, USA.
J Nicholas CochranHudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA.
Diana L MatallanaMedical School, Aging Institute and Psychiatry Department, Neuroscience PhD Program, Pontificia Universidad Javeriana, Bogotá, Colombia.
Daisy AcostaUniversidad Nacional Pedro Henriquez Urena (UNPHU), Santo Domingo, República Dominicana.
Ricardo AllegriDepartment of Cognitive Neurology, Neuropsychiatry and Neuropsychology, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Bianca P Arias-SuárezFaculty of Human Medicine, Postgraduate Section, National University of San Marcos, Lima, Perú.
Bernardo BarraMental Health Service, Clínica Universidad de los Andes, Santiago, Chile.
Maria Isabel BehrensDepartment of Neurology and Psyquiatry, Clínica Alemana-Universidad del Desarrollo, Santiago, Chile.
Sonia M D BruckiCognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo Medical School, University of São Paulo, São Paulo, Brazil.
Geraldo BusattoDepartamento e Instituto de Psiquiatria, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo HCFMUSP, São Paulo, Brazil.
Paulo CaramelliBehavioral and Cognitive Neurology Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Sheila Castro-SuarezAtlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI), University of California San Francisco, San Francisco, California, USA.
Valeria ContrerasHospital Central de las Fuerzas Armadas, Montevideo, Uruguay.
Nilton CustodioUnit of Diagnosis of Cognitive Impairment and Dementia Prevention, Instituto Peruano de Neurociencias, Lima, Perú.
Sergio DansilioDepartment of Neuropsychology, Institut of Neurology, Hospital de Clínicas, Faculty of Medicine, Universidad de la República, Montevideo, Uruguay.
Myriam De la Cruz-PueblaGlobal Brain Health Institute and the Memory and Aging Center, Weill Institute for Neurosciences, Departments of Neurology and Radiology & Biomedical Imaging, University of California, San Francisco (UCSF), San Francisco, California, USA.
Leonardo Cruz de SouzaDepartamento e Instituto de Psiquiatria, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo HCFMUSP, São Paulo, Brazil.
Monica M DiazDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lissette DuqueUnit of Cognitive Diseases, Neuromedicenter, Quito, Ecuador.
Gonzalo A FaríasCenter for Advanced Clinical Research (CICA), Department of Neurology & Neurosurgery and Neuroscience Department, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Sergio T FerreiraInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Nahuel Magrath GuimetAtlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI), University of California San Francisco, San Francisco, California, USA.
Ana KmaidUnit of Cognitive Evaluation, Department of Geriatry ang Gerentology, Hospital de Clínicas, Faculty of Medicine, Universidad de la República, Montevideo, Uruguay.
David LiraUnit of Diagnosis of Cognitive Impairment and Dementia Prevention, Instituto Peruano de Neurociencias, Lima, Perú.
Francisco LoperaGrupo de Neurociencias de Antioquia, Universidad de Antioquia, School of Medicine, Medellín, Colombia.
Beatriz Mar MezaAtlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI), University of California San Francisco, San Francisco, California, USA.
Eliane C MiottoCognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo Medical School, University of São Paulo, São Paulo, Brazil.
Ricardo NitriniCognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo Medical School, University of São Paulo, São Paulo, Brazil.
Alberto NuñezUnit of Cognitive Diseases, Neuromedicenter, Quito, Ecuador.
Santiago O'NeillNeurosciences Institute, Favaloro Foundation University Hospital, Buenos Aires, Argentina.
John OchoaGroup of Neuropsychology and Behavior, Universidad de Antioquia, School of Medicine, Medellín, Colombia.
Maritza Pintado-CaipaAtlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI), University of California San Francisco, San Francisco, California, USA.
Elisa de Paula França ResendeGlobal Brain Health Institute and the Memory and Aging Center, Weill Institute for Neurosciences, Departments of Neurology and Radiology & Biomedical Imaging, University of California, San Francisco (UCSF), San Francisco, California, USA.
Shannon RisacherCenter for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana Alzheimer's Disease Research Center, Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Luz Angela RojasResearch Group, MI Dneuropsy, Universidad Surcolombiana, Neiva, Colombia.
Valentina SabajUnit of Neuropsychogeriatry, Instituto Nacional de Geriatría, Santiago, Chile.
Lucas SchillingNeurology Service, School of Medicine, Pontifical University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Allis F SellekFundAlzheimer, Memory Clinic, Cartago, Costa Rica.
Ana SosaInstituto Nacional de Neurología y Neurocirugía (INNN), Manuel Velasco Suarez, Ciudad de México, México.
Leonel T TakadaCognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo Medical School, University of São Paulo, São Paulo, Brazil.
Antonio L TeixeiraFaculdade Santa Casa BH, Belo Horizonte, Brazil.
Martha Unaucho-PilalumboAtlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI), University of California San Francisco, San Francisco, California, USA.
Claudia Duran-AniotzLatin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.ORCID 0000-0003-2503-8366
Funding
US-South American Initiative for Genetic-Neural-Behavioral Interactions in Human Neurodegenerative ResearchR01AG057234 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Claudia Duran-Aniotz, Agustin M. Ibanez · 2019 to 2026
$6.1MNIA NIH HHS R01 AG057234
Abstract
Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the ongoing work, needs, interests, potential barriers, and opportunities for future studies related to biomarkers. The results show that neuroimaging is the most used biomarker (73%), followed by genetic studies (40%), peripheral fluids biomarkers (31%), and cerebrospinal fluid biomarkers (29%). Regarding barriers in LAC, lack of funding appears to undermine the implementation of biomarkers in clinical or research settings, followed by insufficient infrastructure and training. The survey revealed that despite the above barriers, the region holds a great potential to advance dementia biomarkers research. Considering the unique contributions that LAC could make to this growing field, we highlight the urgent need to expand biomarker research. These insights allowed us to propose an action plan that addresses the recommendations for a biomarker framework recently proposed by regional experts.
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DementiaHumansLatin America
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