Evidence map›Paper›PMID 36098656›Full record

ArticleACS infectious diseases2022

Modulation of Host-Parasite Interactions with Small Molecules Targeting

Youssef Hamway, Kaspar Zimmermann, Marcel J J Blommers, Mariana V Sousa, Cécile Häberli, Shashank Kulkarni, Susanna Skalicky, Matthias Hackl, Marjo Götte, Jennifer Keiser and 3 more

Open access · hybridAbstract read
In one paragraph

Article in ACS infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Unveiling the hemolymphatic miRNome composition of the schistosomiasis vector snailCurrent research in parasitology & vector-borne diseases · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Youssef HamwayInstitute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675Munich, Germany.
Kaspar ZimmermannSaverna Therapeutics AG, Gewerbestrasse 24, 4123Allschwil, Switzerland.
Marcel J J BlommersSaverna Therapeutics AG, Gewerbestrasse 24, 4123Allschwil, Switzerland.
Mariana V SousaInstitute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675Munich, Germany.
Cécile HäberliDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123Allschwil, Switzerland.
Shashank KulkarniEMD Serono Research & Development Institute, Inc. (a Business of Merck KGaA, Darmstadt, Germany), Billerica, Massachusetts01821, United States.
Susanna SkalickyTAmiRNA GmbH, Leberstraße 20, 1110Wien, Austria.
Matthias HacklTAmiRNA GmbH, Leberstraße 20, 1110Wien, Austria.
Marjo GötteSaverna Therapeutics AG, Gewerbestrasse 24, 4123Allschwil, Switzerland.
Jennifer KeiserDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123Allschwil, Switzerland.
Clarissa Prazeres da CostaInstitute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675Munich, Germany.
Thomas SpangenbergGlobal Health Institute of Merck, Ares Trading S.A., a subsidiary of Merck KGaA, Darmstadt, Route de Crassier 1, 1262Eysins, Switzerland.ORCID 0000-0002-5654-8919
Kamal AzzaouiSaverna Therapeutics AG, Gewerbestrasse 24, 4123Allschwil, Switzerland.
Institute of Medical Microbiology and Hygiene · DESwiss Tropical and Public Health Institute · CHMerck (Germany) · DEMerck Serono (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasites use different strategies of communication with their hosts. One communication channel that has been studied in recent years is the use of vesicle microRNAs to influence the host immune system by trematodes. sma-microRNA-10, secreted from

Indexed as

Extracellular VesiclesMicroRNAsAnimalsHost-Parasite InteractionsNF-kappa BSchistosoma mansoniMicroRNAsNF-kappa BFBShost−parasitemicroRNANMRschistosome

Identifiers

PMID36098656
PMCPMC9578036
OpenAlexW4295359524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.