Evidence map›Paper›PMID 36098634›Full record

ArticleeLife2022

Innexin function dictates the spatial relationship between distal somatic cells in the

Theadora Tolkin, Ariz Mohammad, Todd A Starich, Ken C Q Nguyen, David H Hall, Tim Schedl, E Jane Albert Hubbard, David Greenstein

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. TheeLife · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Theadora Tolkin *Kimmel Center for Biology and Medicine at the Skirball Institute, NYU Grossman School of Medicine, New York, United States.ORCID 0000-0003-2174-3885
Ariz Mohammad *Department of Genetics, Washington University School of Medicine, St. Louis, United States.ORCID 0000-0002-2807-412X
Todd A StarichDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States.
Ken C Q NguyenDepartment of Neuroscience, Albert Einstein College of Medicine, The Bronx, United States.ORCID 0000-0002-3479-2611
David H HallDepartment of Neuroscience, Albert Einstein College of Medicine, The Bronx, United States.ORCID 0000-0001-8459-9820
Tim Schedl *Department of Genetics, Washington University School of Medicine, St. Louis, United States.
E Jane Albert Hubbard *Kimmel Center for Biology and Medicine at the Skirball Institute, NYU Grossman School of Medicine, New York, United States.ORCID 0000-0001-5893-7232
David Greenstein *Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States.ORCID 0000-0001-8189-2087
Albert Einstein College of Medicine · USNew York University · USUniversity of Minnesota · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Center for C elegans AnatomyR24OD010943 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DAVID H. HALL, Nathan Schroeder · 2012 to 2026
$9.6M
CENTER FOR CAENORHABDITIS ELGANS ANATOMYR24RR012596 · NCRR · YESHIVA UNIVERSITY · PI HALL, DAVID H. · 1998 to 2011
$8.0M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
CONTROL OF MEIOSIS AND GERMLINE PROLIFERATIONR01GM057173 · NIGMS · VANDERBILT UNIVERSITY · PI GREENSTEIN, DAVID IRWIN · 1998 to 2021
$6.6M
Translational Neuroimaging CoreP30HD071593 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WALKLEY, STEVEN UPSHAW · 2011 to 2015
$5.6M
Stem cell versus meiotic fate decision in C. elegansR01GM100756 · NIGMS · WASHINGTON UNIVERSITY · PI SCHEDL, TIM · 2012 to 2023
$4.2M
The aging stem cell nicheR01AG065672 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI E. Jane Albert Hubbard · 2020 to 2026
$2.2M
The C. elegans Germline: A Test Tube for Cell and Developmental BiologyR35GM144029 · NIGMS · UNIVERSITY OF MINNESOTA · PI David Irwin Greenstein · 2022 to 2026
$2.1M
Diet and Germline ProgenitorsR35GM134876 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HUBBARD, E. JANE ALBERT · 2020 to 2024
$2.1M
120kV Transmission Electron Microscope for a Multi-user Microscopy FacilityS10OD016214 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CONDEELIS, JOHN S · 2014 to 2014
$459k
NCI NIH HHS P30 CA016087NCRR NIH HHS R24 RR012596NIA NIH HHS R01 AG065672NICHD NIH HHS P30 HD071593NIGMS NIH HHS R01 GM057173NIGMS NIH HHS R01 GM100756NIGMS NIH HHS R35 GM134876NIGMS NIH HHS R35 GM144029NIH HHS P40 OD010440NIH HHS R24 OD010943NIH HHS S10 OD016214
6 · The paper itself

Abstract

Gap-junctional signaling mediates myriad cellular interactions in metazoans. Yet, how gap junctions control the positioning of cells in organs is not well understood. Innexins compose gap junctions in invertebrates and affect organ architecture. Here, we investigate the roles of gap-junctions in controlling distal somatic gonad architecture and its relationship to underlying germline stem cells in

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsGerm CellsGonadsStem CellsCaenorhabditis elegans ProteinsC. elegansdevelopmental biologygap junctiongermlineinnexinstem cell

Identifiers

PMID36098634
PMCPMC9473689
OpenAlexW4295350599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.