Evidence map›Paper›PMID 36098533›Full record

ArticleMicrobiology spectrum2022

WYBQ-4: a New Bactericidal Agent against Methicillin-Resistant Staphylococcus aureus.

Shuhan Guan, Hangqian Yu, Hua Xiang, Li Wang, Jingyu Liu, Anfang Wu, Jianze Zheng, Hongbo Dong, Lin Wang, Dacheng Wang

Abstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuhan Guan *College of Animal Science, Jilin Universitygrid.64924.3d, Changchun, China.
Hangqian Yu *College of Animal Science, Jilin Universitygrid.64924.3d, Changchun, China.
Hua XiangCollege of Animal Medicine, Jilin Agricultural University, Changchun, China.
Li WangCollege of Animal Science, Jilin Universitygrid.64924.3d, Changchun, China.
Jingyu LiuCollege of Animal Science, Jilin Universitygrid.64924.3d, Changchun, China.
Anfang WuCollege of Animal Science, Jilin Universitygrid.64924.3d, Changchun, China.
Jianze ZhengCollege of Animal Science, Jilin Universitygrid.64924.3d, Changchun, China.
Hongbo DongSchool of Pharmacy, Chengdu University, Chengdu, China.
Lin WangState Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin Universitygrid.64924.3d, Changchun, China.
Dacheng WangCollege of Animal Science, Jilin Universitygrid.64924.3d, Changchun, China.ORCID 0000-0003-3359-0978

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-resistant pathogen that currently poses a serious threat to global health. Novel antimicrobial agents against MRSA are urgently being developed. In this study, we investigated WYBQ-4, which is an effective antibacterial agent with potent bactericidal activity and bactericidal efficiency against MRSA USA300 and clinical isolate strains. In addition, WYBQ-4 exhibited low cytotoxicity without hemolytic activity according to a safety evaluation. Importantly, WYBQ-4 showed potent

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsCephalosporinsMiceMicrobial Sensitivity TestsPenicillin-Binding ProteinsAnti-Bacterial AgentsCephalosporinsPenicillin-Binding Proteinsbactericidal agentmethicillin-resistant Staphylococcus aureusPBP2aWYBQ-4

Identifiers

PMID36098533
PMCPMC9603521

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.