ArticleJournal of biomechanical engineering2023
Dots-on-Plots: A Web Application to Analyze Stress-Strain Curves From Tensile Tests of Soft Tissue.
Article in Journal of biomechanical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Graphene and TiACS applied bio materials · 2026Article
- Effect of Tear Size and Location on Supraspinatus Tendon Strain During Activities of Daily Living and Physiotherapy.Annals of biomedical engineering · 2024Article
- Age-dependent changes in collagen crosslinks reduce the mechanical toughness of human meniscus.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Modeling fatigue failure in soft tissue using a visco-hyperelastic model with discontinuous damage.Journal of the mechanical behavior of biomedical materials · 2023Article
- Finite element modeling of meniscal tears using continuum damage mechanics and digital image correlation.Scientific reports · 2023Article
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Authors and funding
4 authors.
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Abstract
The calculation of tensile mechanical properties from stress-strain curves is a fundamental step in characterizing material behavior, yet no standardized method exists to perform these calculations for soft tissue. To address this deficiency, we developed a free web application called Dots-on-Plots2 that fully automates the calculation of tensile mechanical properties from stress-strain curves. The analyzed mechanical properties include the strength, strain, and energy at four points of interest (transition, yield, ultimate, and rupture), and the linear modulus. Users of Dots-on-Plots can upload multiple files, view and download results, and adjust threshold settings. This study determined a threshold setting that minimized error when calculating the transition point, where the stress-strain curve "transitions" from a nonlinear "toe" region to a linear region. Using the optimal threshold (2% stress deviation from a linear region fit), Dots-on-Plots calculated the transition strains from twenty tensile experiments of human meniscus to be 0.049 ± 0.007, which nearly matched the known transition strain values of 0.050 ± 0.006 (determined using finite element parameter optimization). The sensitivity of the calculated transition strain to the shape of various stress-strain curves was analyzed using sets of model-generated synthetic data. This free web application offers a convenient and reliable tool to systematically enhance the speed, transparency, and consistency of mechanical analysis across biomedical research groups.
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