Evidence map›Paper›PMID 36098340›Full record

ArticleKorean journal of radiology2022

Clinical and Radiological Features of Diffuse Lacrimal Gland Enlargement: Comparisons among Various Etiologies in 91 Biopsy-Confirmed Patients.

Sae Rom Chung, Gye Jung Kim, Young Jun Choi, Kyung-Ja Cho, Chong Hyun Suh, Soo Chin Kim, Jung Hwan Baek, Jeong Hyun Lee, Min Kyu Yang, Ho-Seok Sa

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Imaging features of lacrimal gland disease.Frontiers in ophthalmology · 2025
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sae Rom ChungDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0003-4219-7166
Gye Jung KimDepartment of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-3663-9653
Young Jun ChoiDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jehee23@gmail.com.ORCID 0000-0001-7098-5042
Kyung-Ja ChoDepartment of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-4911-7774
Chong Hyun SuhDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-4737-0530
Soo Chin KimDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-0511-1696
Jung Hwan BaekDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0003-0480-4754
Jeong Hyun LeeDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-0021-4477
Min Kyu YangDepartment of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0001-5740-1639
Ho-Seok SaDepartment of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. lineblue@hanmail.net.ORCID 0000-0003-3043-7222
Ulsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the clinical and radiological features of various etiologies of chronic diffuse lacrimal gland enlargement. MATERIALS AND

methodsWe retrospectively reviewed 91 consecutive patients who underwent surgical biopsy for chronic diffuse lacrimal gland enlargement and were diagnosed with non-specific dacryoadenitis (DA) (n = 42), immunoglobulin G4-related dacryoadenitis (IgG4-RD) (n = 33), and lymphoma (n = 16). Data on patient demographics, clinical presentation, and CT imaging findings (n = 73) and MRI (n = 43) were collected. The following radiologic features of lacrimal gland enlargement were evaluated: size, unilaterality, wedge sign, angle with the orbital wall, heterogeneity, signal intensity, degree of enhancement, patterns of dynamic contrast-enhanced, and apparent diffusion coefficient value. Radiological features outside the lacrimal glands, such as extra-lacrimal orbital involvement and extra-orbital head and neck involvement, were also evaluated. The clinical and radiological findings were compared among the three diseases.

resultsCompared to the DA and IgG4-RD groups, the lymphoma group was significantly older (mean 59.9 vs. 46.0 and 49.4 years, respectively;

conclusionPatient age, unilaterality, lacrimal gland size, wedge sign, and extra-orbital head and neck involvement differed significantly different between lymphoma, DA, and IgG4-RD. Our results will be useful for the differential diagnosis and proper management of chronic lacrimal gland enlargement.

Indexed as

DacryocystitisImmunoglobulin G4-Related DiseaseLacrimal ApparatusBiopsyHumansImmunoglobulin GRetrospective StudiesImmunoglobulin GDiagnostic imagingImmunoglobulin G4-related diseaseLacrimal apparatusLymphoma

Identifiers

PMID36098340
PMCPMC9523236
OpenAlexW4294577892

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.