Evidence map›Paper›PMID 36098258›Full record

ArticleBritish journal of clinical pharmacology2023

Revisiting the inter-rater reliability of drug treatment assessments according to the STOPP/START criteria.

Naldy Parodi López, Björn Belfrage, Anders Koldestam, Johan Lönnbro, Staffan A Svensson, Susanna M Wallerstedt

Open access · greenAbstract read
In one paragraph

Article in British journal of clinical pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Naldy Parodi LópezDepartment of Pharmacology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-6367-9389
Björn BelfrageNärhälsan Dals-Ed Health Centre, Dals-Ed, Sweden.
Anders KoldestamDepartment of Geriatrics, Sahlgrenska University Hospital, Gothenburg, Sweden.
Johan LönnbroDepartment of Pharmacology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-6917-1076
Staffan A SvenssonDepartment of Pharmacology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-3226-9720
Susanna M WallerstedtDepartment of Pharmacology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-7238-1680
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SE

Funding

Swedish Research Council 2021-01308Swedish Research Council 521-2013-2639Swedish state under the agreement between the Swedish government and the county councils (the ALF agreement) ALFGBG-716941Swedish state under the agreement between the Swedish government and the county councils (the ALF agreement) ALFGBG-965025
6 · The paper itself

Abstract

aimsThe aim of this study is to revisit the inter-rater reliability of drug treatment assessments according to the Screening Tool of Older Persons' Prescriptions (STOPP)/Screening Tool to Alert to Right Treatment (START) criteria.

methodsPotentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) were independently identified by two physicians in two cohorts of older people (I: 200 hip fracture patients, median age 85 years, STOPP/START version 1; II: 302 primary care patients, median age 74 years, STOPP/START version 2). Kappa statistics were used to evaluate inter-rater agreement.

resultsIn cohort I, a total of 782 PIMs/PPOs, related to 68 (78%) out of 87 criteria, were identified by at least one assessor, 500 (64%) of which were discordantly identified by the assessors, that is, by one assessor but not the other. For four STOPP criteria, all PIMs (n = 9) were concordantly identified. In cohort II, 955 PIMs/PPOs, related to 80 (70%) out of 114 criteria, were identified, 614 (64%) of which were discordantly identified. For three STOPP criteria, all PIMs (n = 3) were concordantly identified. For no START criterion, with ≥1 PPO identified, were all assessments concordant. The kappa value for PIM/PPO identification was 0.52 in both cohorts. In cohort II, the kappa was 0.37 when criteria regarding influenza and pneumococcal vaccines were excluded. Further analysis of discordantly identified PIMs/PPOs revealed methodological aspects of importance, including the data source used and criteria wording.

conclusionsWhen the STOPP/START criteria are applied in PIM/PPO research, reliability seems to be an issue not encountered in previous reliability studies.

Indexed as

Hip FracturesPotentially Inappropriate Medication ListAgedAged, 80 and overHumansInappropriate PrescribingPrescriptionsReproducibility of Resultsassessmentmethodologypharmacoepidemiologypharmacotherapyquality

Identifiers

PMID36098258
PMCPMC10092534
OpenAlexW4295350563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.