Evidence map›Paper›PMID 36098244›Full record

ArticleVeterinary medicine and science2022

Immunophenotypic and molecular profile of cancer stem-cell markers in ex vivo canine transmissible venereal tumour (CTVT).

Fabrizio Grandi, Hélio Amante Miot, Rafael Malagoli Rocha, Cristina Massoco Salles Gomes, Nicolle Queiroz-Hazarbassanov, Luis Mauricio Montoya-Florez, Bruno Cogliati, Noeme Sousa Rocha

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Fabrizio GrandiDepartment of Pathology, Botucatu Medical School, Universidade Estadual Paulista, UNESP Botucatu, São Paulo, Brazil.
Hélio Amante MiotDepartment of Dermatology and Radiotherapy, Botucatu Medical School, Universidade Estadual Paulista, UNESP, Botucatu, São Paulo, Brazil.
Rafael Malagoli RochaDepartment of Pathology, A.C. Camargo Cancer Hospital, São Paulo, Brazil.
Cristina Massoco Salles GomesDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, São Paulo, Brazil.
Nicolle Queiroz-HazarbassanovDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, São Paulo, Brazil.
Luis Mauricio Montoya-FlorezDepartment of Animal Health, Universidad Nacional de Colombia, Bogotá, Colombia.ORCID 0000-0002-5198-7998
Bruno CogliatiDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, São Paulo, Brazil.
Noeme Sousa RochaDepartment of Pathology, Botucatu Medical School, Universidade Estadual Paulista, UNESP Botucatu, São Paulo, Brazil.
Universidade de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BRAC Camargo Hospital · BRUniversidad Nacional de Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies have attempted to characterise the origin of canine transmissible venereal tumour (CTVT). However, the participation of cancer stem cells (CSC) has not been reported

objectivesHerein we describe the expression patterns of CSC markers CD44, CD34, CD90 and CD133 in CTVT

methodsThirty-eight samples were selected and assessed through flow cytometry and immunohistochemistry RESULTS AND

conclusionsTwenty-two tumours were classified as plasmacytoid and 16 as mixed. Almost all tumours showed high CD44 and low CD34 levels. CD133 and CD90 expression varied among tumours. Cytological groups did not differ in the proportion of CSC markers. Our results suggest that CSC subpopulations might participate in CTVT.

Indexed as

Dog DiseasesNeoplasmsVenereal Tumors, VeterinaryAnimalsDogsImmunohistochemistryNeoplastic Stem Cellsdogflow cytometryimmunohistochemistrylymphocytoid

Identifiers

PMID36098244
PMCPMC9677402
OpenAlexW4295346245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.