Evidence map›Paper›PMID 36098058›Full record

ArticleCirculation. Heart failure2022

Sarcopenic Obesity Is Associated With Reduced Cardiorespiratory Fitness Compared With Nonsarcopenic Obesity in Patients With Heart Failure With Reduced Ejection Fraction.

Hayley E Billingsley, Marco Giuseppe Del Buono, Justin M Canada, Youngdeok Kim, Juan Ignacio Damonte, Cory R Trankle, Geza Halasz, Virginia Mihalick, Alessandra Vecchié, Roshanak R Markley and 10 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  7. Frailty and Cardiovascular Risk.European cardiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 5 countries.

Hayley E BillingsleyDepartment of Kinesiology & Health Sciences, College of Humanities and Sciences (H.E.B., Y.K., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0002-6239-467X
Marco Giuseppe Del BuonoVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Justin M CanadaVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Youngdeok KimDepartment of Kinesiology & Health Sciences, College of Humanities and Sciences (H.E.B., Y.K., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0002-6134-0100
Juan Ignacio DamonteVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Cory R TrankleVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0002-3891-7004
Geza HalaszCardiac Unit, G. da Saliceto Hospital, AUSL Piacenza and University of Parma, Italy (G.H.).ORCID 0000-0001-7220-123X
Virginia MihalickVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Alessandra VecchiéVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0003-0410-5996
Roshanak R MarkleyVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0001-9676-3333
Dinesh KadariyaVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Edoardo BressiVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0002-8080-6842
Horacio Medina de ChazalVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Juan Guido ChiabrandoVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0002-2128-8280
James MbualunguVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Jeremy TurlingtonVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.
Ross ArenaHealthy Living for Pandemic Event Protection Network, Chicago, IL (R.A.).ORCID 0000-0002-6675-1996
Benjamin W Van TassellVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0003-0688-4487
Antonio AbbateVCU Pauley Heart Center (H.E.B., M.G.D.B., J.M.C., J.I.D., C.R.T., V.M., A.V., R.R.M., D.K., E.B., H.M.d.C., J.G.C., J.M., J.T., B.W.V.T., A.A., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0002-1930-785X
Salvatore CarboneDepartment of Kinesiology & Health Sciences, College of Humanities and Sciences (H.E.B., Y.K., S.C.), Virginia Commonwealth University, Richmond.ORCID 0000-0002-8163-0527
Virginia Commonwealth University · USUnited States Nuclear Regulatory Commission · USGuglielmo da Saliceto Hospital · ITIllinois College · USMACOM (United States) · US

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
The Effects of Interleukin-1 Blockade On Exercise Capacity In Patients With Recently Decompensated Systolic Heart FailureR33HL139943 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI ABBATE, ANTONIO, VAN TASSELL, BENJAMIN W · 2019 to 2022
$2.2M
The Effects of Interleukin-1 Blockade On Exercise Capacity In Patients With Recently Decompensated Systolic Heart FailureR61HL139943 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI ABBATE, ANTONIO, VAN TASSELL, BENJAMIN W · 2018 to 2018
$533k
NCATS NIH HHS UL1 TR002649NHLBI NIH HHS R33 HL139943NHLBI NIH HHS R61 HL139943
6 · The paper itself

Abstract

backgroundSarcopenia impairs cardiorespiratory fitness (CRF) in patients with heart failure with reduced ejection fraction (HFrEF). Obesity has also been shown to impair CRF; however, the effects of sarcopenia on CRF in patients with obesity and HFrEF are unknown. The aim of this analysis was to examine differences in CRF between patients with sarcopenic obesity (SO) and non-SO (NSO) with HFrEF. We also assessed associations between skeletal muscle mass index (SMMI) and CRF.

methodsForty patients with HFrEF and obesity underwent cardiopulmonary exercise testing to collect measures of CRF including peak oxygen consumption (VO

resultsNearly half (43% [n=17]) of patients had SO. Patients with SO had a lower SMMI than those with NSO, and no differences in fat mass index were observed between groups. Those with SO achieved a lower absolute peak VO

conclusionsIn patients with HFrEF and obesity, sarcopenia, defined as low SMMI, is associated with a clinically significant reduction in CRF, independent of adiposity.

Indexed as

Cardiorespiratory FitnessHeart FailureSarcopeniaExercise TestHumansObesityOxygenOxygen ConsumptionStroke VolumeOxygencardiorespiratory fitnessheart failureobesityrisksarcopenia

Identifiers

PMID36098058
PMCPMC9588574
OpenAlexW4295512286

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.