Evidence map›Paper›PMID 36098047›Full record

ArticleEuropean journal of preventive cardiology2022

Frequent vegetable consumption is inversely associated with hypertension among indigenous Africans.

Onoja Matthew Akpa, Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Tinashe Chikowore, Shukri F Mohamed, Fred Sarfo, Rufus Akinyemi, Albert Akpalu, Kolawole Wahab, Reginald Obiako and 14 more

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Article in European journal of preventive cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Onoja Matthew AkpaDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.ORCID 0000-0002-5201-512X
Akinkunmi Paul OkekunleDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.ORCID 0000-0003-4825-4934
Osahon Jeffery AsowataDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.
Tinashe ChikoworeMRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2000, South Africa.
Shukri F MohamedHealth and Well-Being Program, African Population and Health Research Center, 00100, Nairobi, Kenya.
Fred SarfoDepartment of Medicine, Kwame Nkrumah University of Science and Technology, 00000, Kumasi, Ghana.
Rufus AkinyemiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.
Albert AkpaluDepartment of Medicine, University of Ghana Medical School, P.O. Box LG 1181, Legon, Accra, Ghana.
Kolawole WahabDepartment of Medicine, University of Ilorin, 240003, Ilorin, Nigeria.
Reginald ObiakoDepartment of Medicine, Ahmadu Bello University, 810107, Zaria, Nigeria.
Morenikeji KomolafeDepartment of Medicine, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.
Lukman OwolabiDepartment of Medicine, Aminu Kano Teaching Hospital, 700233, Kano, Nigeria.
Godwin O OsaigbovoDepartment of Internal Medicine, Jos University Teaching Hospital Jos, 930241, Jos, Nigeria.
Godwin OgboleDepartment of Radiology, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.
Hemant K TiwariDepartment of Biostatistics, School of Public Health, the University of Alabama at Birmingham, Birmingham, 35233 AL, USA.
Joshua AkinyemiDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.
Adekunle FakunleDepartment of Medicine, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.
Ezinne UvereDepartment of Medicine, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.
Abiodun M AdeoyeInstitute of Cardiovascular Diseases, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.
Daniel LacklandDepartment of Neurology, Medical University of South Carolina, Charleston, 29425 SC, USA.
Donna K ArnettDepartment of Epidemiology, College of Public Health, University of Kentucky, Lexington, 40536 KY, USA.
Bruce OvbiageleWeill Institute for Neurosciences, School of Medicine, University of California San-Francisco, San-Francisco, 94143 CA, USA.
Michèle RamsaySydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2000, South Africa.ORCID 0000-0002-4156-4801
Mayowa OwolabiDepartment of Medicine, College of Medicine, University of Ibadan, 200284, Ibadan, Nigeria.ORCID 0000-0003-1146-3070

Funding

Shared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2M
H3Africa Administrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in AfricaU24HG009780 · NHGRI · UNIVERSITY OF CAPE TOWN · PI SKELTON, MICHELLE · 2017 to 2022
$4.8M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
CNV And Stroke (CaNVAS)R01NS114045 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI COLE, JOHN W. · 2020 to 2024
$2.6M
African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES)R01NS115944 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2020 to 2025
$2.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
Training Africans to Lead and Execute Neurological Trials & Studies (TALENTS)D43TW012030 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OVBIAGELE, BRUCE · 2021 to 2025
$1.2M
African Neurobiobank for Precision Stroke Medicine - (ELSI) ProjectU01HG010273 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI AKINYEMI, RUFUS OLUSOLA, ARULOGUN, OYEDUNNI SOLA · 2018 to 2022
$512k
Sub-Saharan Africa Conference on Stroke (SSACS) ConferenceR13NS115395 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE · 2020 to 2020
$50k
FIC NIH HHS D43 TW012030NHGRI NIH HHS U01 HG010273NHGRI NIH HHS U24 HG009780NHGRI NIH HHS U54 HG006938NHGRI NIH HHS U54 HG007479NINDS NIH HHS R01 NS107900NINDS NIH HHS R01 NS114045NINDS NIH HHS R01 NS115944NINDS NIH HHS R13 NS115395Wellcome TrustWellcome Trust 214205/Z/18/Z
6 · The paper itself

Abstract

aimsThe relationship between vegetable consumption and hypertension occurrence remains poorly characterized in sub-Saharan Africa. This study assessed the association of vegetable consumption with odds of hypertension among indigenous Africans. METHODS AND

resultsWe harmonized data on prior vegetable consumption and hypertension occurrence (defined as one of the following conditions; systolic blood pressure ≥140 or diastolic blood pressure ≥90 mmHg or previous diagnosis or use of antihypertensive medications) from 16 445 participants across five African countries (Nigeria, South Africa, Kenya, Ghana and Burkina Faso) in the Stroke Investigative Research and Educational Network and Africa Wits-INDEPTH partnership for Genomic studies. Vegetable consumption (in servings/week) was classified as 'low' (<6). 'moderate' (6-11), 'sufficient' (12-29), and 'high' (≥30). Odds ratios (ORs) and 95% confidence interval (CI) of hypertension were estimated by categories of vegetable consumption (using 'low' consumption as reference), adjusting for sex, age in years, family history of cardiovascular diseases, education, smoking, alcohol use, physical inactivity, body mass index, diabetes mellitus and dyslipidaemia using logistic regressions at P < 0.05. The mean age of participants was 53.0 ( ± 10.7) years, and 7552 (45.9%) were males, whereas 7070 (42.9%) had hypertension. In addition, 6672(40.6%) participants had 'low' vegetable consumption, and 1758(10.7%) had 'high' vegetable consumption. Multivariable-adjusted OR for hypertension by distribution of vegetable consumption (using 'low' consumption as reference) were 1.03 (95% CI: 0.95, 1.12) for 'moderate' consumption; 0.80 (0.73, 0.88) for 'sufficient', and 0.81 (0.72, 0.92) for 'high' consumption, P-for-trend <0.0001.

conclusionIndigenous Africans who consumed at least 12 servings of vegetables per week were less likely to be found hypertensive, particularly among males and young adults.

Indexed as

Cardiovascular DiseasesHypertensionAdultAfrican PeopleDietFemaleFruitHumansMaleMiddle AgedRisk FactorsVegetablesYoung AdultAWI-GenCardiovascular DiseasesDietH3AfricaHypertensionSIRENVegetables

Identifiers

PMID36098047
PMCPMC9977189

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.