Evidence map›Paper›PMID 36097528›Full record

ArticleInfection and drug resistance2022

Trend of Malaria Burden Among Residents of Kisii County, Kenya After More Than a Decade Usage of Artemisinin Combined Therapies, 11-Year Laboratory Based Retrospective Study.

Josephat Nyabayo Maniga, Mong'are Samuel, Masai Rael, John Odda, Odoki Martin, Ibrahim Ntulume, Pacifica Bwogo, Wilberforce Mfitundinda, Saheed Adekunle Akinola

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Josephat Nyabayo ManigaDepartment of Biological Sciences, Kisii University, Kisii, Kenya.ORCID 0000-0002-0173-6277
Mong'are SamuelSchool of Health Sciences, Kisii University, Kisii, Kenya.ORCID 0000-0001-8703-2301
Masai RaelDepartment of Biological Sciences, Kisii University, Kisii, Kenya.
John OddaSchool of Pharmacy, Kampala International University Western Campus, Bushenyi, Uganda.
Odoki MartinDepartment of Microbiology and Immunology, Kampala International University Western Campus, Bushenyi, Uganda.
Ibrahim NtulumeDepartment of Microbiology and Immunology, Kampala International University Western Campus, Bushenyi, Uganda.ORCID 0000-0002-3157-6251
Pacifica BwogoDepartment of Biological Sciences, Kisii University, Kisii, Kenya.
Wilberforce MfitundindaCollege of Medicine, Health and Life Sciences, School of Medicine, King Ceasor University, Kampala, Uganda.ORCID 0000-0003-1910-1066
Saheed Adekunle AkinolaDepartment of Microbiology and Immunology, Kampala International University Western Campus, Bushenyi, Uganda.ORCID 0000-0002-6520-8609
Kampala International University · UGKisii University · KESt. Augustine International University · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Malaria remains a major vector borne disease globally, with the majority of the casualties reported in Africa. Despite this fact, there is drastic reduction in malaria infection using Artemisinin combined therapies (ACTs). Malaria is characterized by significant inconsistency in different geographical locations due to different confounding factors. There is need to identify zone-specific malaria trends and interventions to completely eliminate the disease. Thus the study was aimed at assessing the 11-year trend of microscopically confirmed malaria cases in Kisii County, Kenya, so as to devise area-specific evidence-based interventions, informed decisions, and to track the effectiveness of malaria control programs. Methods: This was a retrospective study carried out to determine 11-year malaria trend rates centered on the admission and laboratory records from health facilities located at four Sub-Counties in Kisii County, Kenya. Parasitological positivity rates of malaria were determined by comparing with the register records in health facilities which recorded confirmed malaria cases with the total number of monthly admissions over the entire year. Data was analyzed by using descriptive tools and chi-square test. Results: There were 36,946 suspect cases, with 8449 (22.8%) confirmed malaria cases reported in this study. The overall malaria slide positivity rate over the last 11 years in the study area was 22.6%. The months of April and August showed the largest number of malaria cases (63%). The age group of ≥18 years contained the most positive confirmed cases, having a prevalence rate of 2953 (35.45%). Out of the confirmed malaria cases, 2379 (28.1%) were males and 6070 (71.9%) were females The highest malaria prevalence rate was recorded in 2014, with Marani Sub-County recording the highest positivity rate of 37.94%. Conclusion: From the observed trends, malaria prevalence and transmission still remains stable in the study area. Thus more interventions need to be scaled up.

Indexed as

ACTsartemisinin combined therapiesmalaria burdenretrospective

Identifiers

PMID36097528
PMCPMC9464030
OpenAlexW4294687110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.