Microflows in two-generation alveolar cells at an acinar bifurcation.

Yue Yang, Weitao Bai, Jun Dong, Huimin Lv, Yonggang Zhu

Open access · greenAbstract read

In one paragraph

Article in Biomicrofluidics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 41% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yue YangCenter for Microflows and Nanoflows, School of Mechanical Engineering and Automation, Harbin Institute of Technology, Shenzhen 518055, China.ORCID 0000-0002-2395-286X

Weitao BaiCenter for Microflows and Nanoflows, School of Mechanical Engineering and Automation, Harbin Institute of Technology, Shenzhen 518055, China.

Jun DongCenter for Microflows and Nanoflows, School of Mechanical Engineering and Automation, Harbin Institute of Technology, Shenzhen 518055, China.ORCID 0000-0002-4959-6605

Huimin LvCenter for Microflows and Nanoflows, School of Mechanical Engineering and Automation, Harbin Institute of Technology, Shenzhen 518055, China.

Yonggang ZhuCenter for Microflows and Nanoflows, School of Mechanical Engineering and Automation, Harbin Institute of Technology, Shenzhen 518055, China.

Harbin Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alveolus is a basic functional unit of the human respiratory system, and the airflow in the alveoli plays an important role in determining the transport and deposition of particulate matter, which is crucial for inhaled disease diagnosis and drug delivery. In the present study, taking advantage of the precise control ability of the microfluidic technique, a rhythmically expanding alveolar chip with multiple alveoli in two generations is designed and both the geometric and kinematic similarities are matched with the real human respiration system. With the help of a micro-PIV measurement system, the microflow patterns inside each alveolus can be studied. The observed vortex and radial flow patterns and the discovery of stagnant saddle points are similar to those captured in our previous platform with only one alveolus [Lv

Identifiers

PMID36097514

DOI10.1063/5.0098302

PMCPMC9451617

OpenAlexW4294771584

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.