Evidence map›Paper›PMID 36097458›Full record

ArticleHeart rhythm O22022

Predicting permanent pacemaker implantation following transcatheter aortic valve replacement: A contemporary meta-analysis of 981,168 patients.

Anan A Abu Rmilah, Hossam Al-Zu'bi, Ikram-Ul Haq, Asil H Yagmour, Suhaib A Jaber, Adham K Alkurashi, Ibraheem Qaisi, Gurukripa N Kowlgi, Yong-Mei Cha, Siva Mulpuru and 2 more

Abstract read
In one paragraph

Article in Heart rhythm O2, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Obesity and Transcatheter Aortic Valve Replacement.Journal of cardiovascular development and disease · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anan A Abu RmilahDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Hossam Al-Zu'biDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Ikram-Ul HaqDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Asil H YagmourAl Quds University School of Medicine, Palestine.
Suhaib A JaberDepartment of Internal Medicine, Al Hamadi Hospital, Riyadh, Saudi Arabia.
Adham K AlkurashiDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Ibraheem QaisiAn-Najah National University School of Medicine, Palestine.
Gurukripa N KowlgiDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Yong-Mei ChaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Siva MulpuruDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Christopher V DeSimoneDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Abhishek J DeshmukhDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Heart block requiring permanent pacemaker (PPM) implantation is a relatively frequent complication of transcatheter aortic valve replacement (TAVR). Objective: The purpose of this study was to perform a contemporary meta-analysis to provide an updated assessment of clinically useful predictors of PPM implantation post-TAVR. Methods: Medline and EMBASE searches were performed to include all studies reporting PPM post-TAVR between 2015 and 2020. Pertinent data were extracted from the studies for further analysis. RevMan was used to create forest plots and calculate risk ratios (RRs). Results: We evaluated 41 variables from 239 studies with a total of 981,168 patients. From this cohort, 17.4% received a PPM following TAVR. Strong predictors for PPM implant were right bundle branch block (RBBB) (RR 3.12; Conclusion: Male gender, age ≥80 years, FDAVB, RBBB, AF, DM, CKD, Medtronic CoreValve, transfemoral TAVR, increased LVOT, and aortic annulus diameter were significant predictors of post-TAVR PPM implantation. Preprocedural assessment should consider these factors to guide clinical decision-making before TAVR. Validation of our scoring system is warranted.

Indexed as

Atrioventricular blockBundle branch blockConduction disturbancePacemakerTranscatheter aortic valve replacement

Identifiers

PMID36097458
PMCPMC9463692

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.