Evidence map›Paper›PMID 36097314›Full record

ArticleJournal of cardiovascular translational research2023

Collagen Molecular Damage is a Hallmark of Early Atherosclerosis Development.

Kelly A Smith, Allen H Lin, Alexander H Stevens, S Michael Yu, Jeffrey A Weiss, Lucas H Timmins

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. How Advanced Is Nanomedicine for Atherosclerosis?International journal of nanomedicine · 2025
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly A SmithDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, 84112, USA.
Allen H LinDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, 84112, USA.
Alexander H StevensDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, 84112, USA.
S Michael YuDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, 84112, USA.
Jeffrey A WeissDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, 84112, USA.
Lucas H TimminsDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, 84112, USA. lucas.timmins@utah.edu.ORCID 0000-0002-8707-8120

Funding

Targeting Collagen Mechanical Damage using Collagen Hybridizing PeptidesR01AR071358 · NIAMS · UNIVERSITY OF UTAH · PI WEISS, JEFFREY A., YU, MICHAEL S · 2018 to 2022
$1.9M
In situ imaging of collagen degradation activity in multiple myeloma and lung fibrosis mouse modelR21OD026618 · OD · UNIVERSITY OF UTAH · PI YOON, DONGHOON, YU, MICHAEL S · 2019 to 2020
$430k
NIH HHS R21 OD026618
6 · The paper itself

Abstract

Remodeling of extracellular matrix proteins underlies the development of cardiovascular disease. Herein, we utilized a novel molecular probe, collagen hybridizing peptide (CHP), to target collagen molecular damage during atherogenesis. The thoracic aorta was dissected from ApoE

Indexed as

AtherosclerosisAnimalsAorta, ThoracicApolipoproteins ECollagenDiet, High-FatDisease Models, AnimalMiceMice, KnockoutApolipoproteins ECollagenApolipoproteinsAtherogenesisCollagen mimetic peptideCollagen remodelingMechanobiology

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.