ArticleSurgical endoscopy2023
Per-oral endoscopic myotomy for the treatment of non-achalasia esophageal dysmotility disorders: experience from a single high-volume center.
Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Efficacy and safety of per-oral endoscopic myotomy in non-achalasia esophageal motility disorders: a systematic review and meta-analysis.Esophagus : official journal of the Japan Esophageal Society · 2024Pooled it
- Development of a diagnostic model for esophageal achalasia assessed by esophageal high-resolution manometry using artificial intelligence.Experimental and therapeutic medicine · 2026Article
- Presence of type 1 hiatal hernia affects the clinical efficacy of per-oral endoscopic myotomy.Surgical endoscopy · 2025Article
- Impact of hiatal hernia on periprocedural outcomes following peroral endoscopic myotomy: a nationwide retrospective study.Surgical endoscopy · 2025Article
- Surgical management of achalasia.Abdominal radiology (New York) · 2025Review
- Comparing peroral endoscopic myotomy and laparoscopic Heller myotomy for esophageal motility disorders: Nationwide cohort study.Endoscopy international open · 2025Article
- The effect of per-oral endoscopic myotomy by achalasia subtype as measured by impedance planimetry.Surgical endoscopy · 2024Article
- Impedance planimetry during per-oral endoscopic myotomy is associated with decreased inadvertent capnoperitoneum.Surgical endoscopy · 2024Article
- Precision Endoscopy in Peroral Myotomies for Motility Disorders of the Upper Gastrointestinal Tract: Current Insights and Prospective Avenues-A Comprehensive Review.Life (Basel, Switzerland) · 2023Review
- What role does the submucosa play in the pathophysiology and treatment of achalasia? An analysis of impedance planimetry during POEM.Surgical endoscopy · 2023Article
- [Interventional endoscopy in gastroenterology].Innere Medizin (Heidelberg, Germany) · 2023Article
- Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child.Frontiers in pediatrics · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAchalasia is a rare disorder of esophageal motility that induces progressive intolerance to oral intake. Other esophageal dysmotility disorders include esophagogastric junction outflow obstruction (EGJOO), distal esophageal spasm (DES), hypercontractile esophagus (HE), and other minor disorders of peristalsis (MDP) and can present similarly to achalasia despite different pathophysiologies. Prior studies have demonstrated the safety and efficacy of POEM in the treatment of achalasia, but little is reported regarding POEM's role in treating non-achalasia esophageal dysmotility disorders (NAEDD). This study aims to assess the safety and efficacy of POEM in the treatment of NAEDD. STUDY
designThis is a retrospective review of consecutive POEM cases from June 1, 2011, to February 1, 2021. NAEDD were characterized according to the Chicago classification. Primary outcome measure was the resolution of preoperative symptoms. Secondary outcomes include preoperative diagnosis, myotomy length, conversion to laparoscopic or open procedure, operative time, and length of stay (LOS). Technical success was defined as the completion of an 8 cm myotomy including the esophagogastric junction (EGJ) and extending 2 cm distal to the EGJ. Clinical success was defined as a postoperative Eckardt score ≤ 3.
resultsOf 124 cases of POEM performed during the study period, 17 were performed for NAEDD. Technical success was achieved in all 17 patients (100%). Of the fifteen patients that had documented postoperative Eckardt scores, 13 were ≤ 3, achieving a clinical success rate of 87%. Subgroup analysis (HE/MDP/DES vs. EGJOO) showed no significant differences in the preoperative or postoperative Eckardt scores between groups, and both groups demonstrated a significant decrease in Eckardt scores after POEM. No cases were aborted for technical or clinical reasons, and there were no adverse outcomes.
conclusionPOEM is a safe and efficacious treatment modality for NAEDD. Further work is needed to develop optimal treatment strategies for this complex group of diseases.
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