Evidence map›Paper›PMID 36097028›Full record

ArticleScientific reports2022

Bioengineering of CuO porous (nano)particles: role of surface amination in biological, antibacterial, and photocatalytic activity.

Mojtaba Bagherzadeh, Moein Safarkhani, Amir Mohammad Ghadiri, Mahsa Kiani, Yousef Fatahi, Fahimeh Taghavimandi, Hossein Daneshgar, Nikzad Abbariki, Pooyan Makvandi, Rajender S Varma and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 5 countries.

Mojtaba BagherzadehDepartment of Chemistry, Sharif University of Technology, Tehran, Iran. bagherzadeh@sharif.edu.
Moein SafarkhaniDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Amir Mohammad GhadiriDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Mahsa KianiDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Yousef FatahiNanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, 14155-6451, Iran.
Fahimeh TaghavimandiDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Hossein DaneshgarDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Nikzad AbbarikiDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Pooyan MakvandiIstituto Italiano di Tecnologia, Centre for Materials Interfaces, Pontedera, 56025, Pisa, Italy.
Rajender S VarmaRegional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute, Palacky University, Olomouc, Slechtitel, ů 11, 783 71, Olomouc, Czech Republic.
Navid RabieeSchool of Engineering, Macquarie University, Sydney, NSW, 2109, Australia.
Sharif University of Technology · IRItalian Institute of Technology · ITMacquarie University · AUPalacký University Olomouc · CZTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology is one of the most impressive sciences in the twenty-first century. Not surprisingly, nanoparticles/nanomaterials have been widely deployed given their multifunctional attributes and ease of preparation via environmentally friendly, cost-effective, and simple methods. Although there are assorted optimized preparative methods for synthesizing the nanoparticles, the main challenge is to find a comprehensive method that has multifaceted properties. The goal of this study has been to synthesize aminated (nano)particles via the Rosmarinus officinalis leaf extract-mediated copper oxide; this modification leads to the preparation of (nano)particles with promising biological and photocatalytic applications. The synthesized NPs have been fully characterized, and biological activity was evaluated in antibacterial assessment against Bacillus cereus as a model Gram-positive and Pseudomonas aeruginosa as a model Gram-negative bacterium. The bio-synthesized copper oxide (nano)particles were screened by MTT assay by applying the HEK-293 cell line. The aminated (nano)particles have shown lower cytotoxicity (~ 21%), higher (~ 50%) antibacterial activity, and a considerable increase in zeta potential value (~ + 13.4 mV). The prepared (nano)particles also revealed considerable photocatalytic activity compared to other studies wherein the dye degradation process attained 97.4% promising efficiency in only 80 min and just 7% degradation after 80 min under dark conditions. The biosynthesized copper oxide (CuO) (nano)particle's biomedical investigation underscores an eco-friendly synthesis of (nano)particles, their noticeable stability in the green reaction media, and impressive biological activity.

Indexed as

CopperMetal NanoparticlesAminationAnti-Bacterial AgentsBioengineeringHEK293 CellsHumansOxidesPorosityAnti-Bacterial AgentsCoppercupric oxideOxides

Identifiers

PMID36097028
PMCPMC9467996
OpenAlexW4295422463

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.