Evidence map›Paper›PMID 36097014›Full record

ReviewNature communications2022

The importance of antimicrobial resistance in medical mycology.

Neil A R Gow, Carolyn Johnson, Judith Berman, Alix T Coste, Christina A Cuomo, David S Perlin, Tihana Bicanic, Thomas S Harrison, Nathan Wiederhold, Mike Bromley and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 204 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Climate change and antimicrobial resistance.Nature reviews. Microbiology · 2026
    Review
  5. Beyond intrinsic resistance: novel insights into the emergence and management of resistance acquired in Candida auris upon antifungal exposure.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  6. Review
  7. Article
  8. Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  9. Review
  10. Trends in antifungal use characteristics in primary care in Spain, 2019 to 2024: a nationwide study.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Observational
  11. Article
  12. Essential oil of ocimum gratissimum as a natural fungicide against pathogenic fungi of fruit crops and molecular docking studies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Neil A R GowMRC Centre for Medical Mycology, School of Biosciences, University of Exeter, Geoffrey Pope Building, Exeter, EX4 4QD, UK. N.Gow@exeter.ac.uk.ORCID 0000-0002-2776-5850
Carolyn JohnsonMedical Research Council, Polaris House, Swindon, SN2 1FL, UK. Carolyn.Johnson@mrc.ukri.org.ORCID 0000-0002-0494-8136
Judith BermanShmunis School of Biomedical and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, 418 Britannia Building, Ramat Aviv, 69978, Israel.
Alix T CosteMicrobiology Institute, University Hospital Lausanne, rue du Bugnon 48, 1011, Lausanne, Switzerland.ORCID 0000-0001-9481-9778
Christina A Cuomo(CAC) Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.ORCID 0000-0002-5778-960X
David S PerlinCenter for Discovery and Innovation, Hackensack Meridian health, Nutley, NJ, 07110, USA.ORCID 0000-0002-1268-5524
Tihana BicanicInstitute of Infection and Immunity, St George's University of London, London, SW17 0RE, UK.ORCID 0000-0002-2676-838X
Thomas S HarrisonMRC Centre for Medical Mycology, School of Biosciences, University of Exeter, Geoffrey Pope Building, Exeter, EX4 4QD, UK.
Nathan WiederholdDepartment of Pathology and Laboratory Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.ORCID 0000-0002-2225-5122
Mike BromleyManchester Fungal Infection Group, Division of Evolution, Infection, and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, CTF Building, 46 Grafton Street, Manchester, M13 9NT, UK.ORCID 0000-0002-7611-0201
Tom ChillerCenter for Disease Control and Prevention Mycotic Disease Branch 1600 Clifton Rd, MSC-09, Atlanta, 30333, GA, USA.
Keegan EdgarCenter for Disease Control and Prevention Mycotic Disease Branch 1600 Clifton Rd, MSC-09, Atlanta, 30333, GA, USA.
Centers for Disease Control and Prevention · USSt George's, University of London · GBBroad Institute · USCenter for Discovery · USTel Aviv University · ILThe University of Texas Health Science Center at San Antonio · USUK Research and Innovation · GBUniversity of Exeter · GBUniversity of Manchester · GB

Funding

Critical Factors Influencing Echinocandin Resistance in CandidaglabrataR01AI109025 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI PERLIN, DAVID S · 2014 to 2025
$9.8M
Department of HealthMedical Research Council MR/N006364/2MRF_ MRF-160-0009-ELP-BICA-C0802NIAID NIH HHS R01 AI109025Wellcome TrustWellcome Trust 101873/Z/13/ZWellcome Trust 200208/A/15/ZWellcome Trust 208396/Z/17/ZWellcome Trust 215599/Z/19/ZWellcome Trust 219551/Z/19/Z
6 · The paper itself

Abstract

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global health care priority. Some analyses, including the O'Neill report, have predicted that deaths due to drug-resistant bacterial infections may eclipse the total number of cancer deaths by 2050. Although fungal infections remain in the shadow of public awareness, total attributable annual deaths are similar to, or exceeds, global mortalities due to malaria, tuberculosis or HIV. The impact of fungal infections has been exacerbated by the steady rise of antifungal drug resistant strains and species which reflects the widespread use of antifungals for prophylaxis and therapy, and in the case of azole resistance in Aspergillus, has been linked to the widespread agricultural use of antifungals. This review, based on a workshop hosted by the Medical Research Council and the University of Exeter, illuminates the problem of antifungal resistance and suggests how this growing threat might be mitigated.

Indexed as

COVID-19 Drug TreatmentMycosesAnti-Bacterial AgentsAntifungal AgentsDrug Resistance, BacterialHumansMycologySARS-CoV-2Anti-Bacterial AgentsAntifungal Agents

Identifiers

PMID36097014
PMCPMC9466305
OpenAlexW4295347063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.