Evidence map›Paper›PMID 36096758›Full record

ArticleBMC public health2022

Zero knowledge and high interest in the use of long-acting injectable pre-exposure prophylaxis (PrEP) among adolescent men who have sex with men and transgender women in two capital cities in Brazil.

Leo Pedrana, Laio Magno, Eliana Miura Zucchi, Luís Augusto Vasconcelos da Silva, Dulce Ferraz, Alexandre Grangeiro, Marcelo Castellanos, Sandra Assis Brasil, Inês Dourado

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Leo PedranaInstituto de Saúde Coletiva, Universidade Federal da Bahia, R. Basílio da Gama, s/n - Canela, Salvador, BA, CEP: 40110-040, Brazil. leo.pedrana@gmail.com.
Laio MagnoInstituto de Saúde Coletiva, Universidade Federal da Bahia, R. Basílio da Gama, s/n - Canela, Salvador, BA, CEP: 40110-040, Brazil.
Eliana Miura ZucchiPrograma de Pós-Graduação em Saúde Coletiva, Mestrado Profissional em Psicologia, Desenvolvimento e Políticas Públicas, Universidade Católica de Santos, Santos, Brazil.
Luís Augusto Vasconcelos da SilvaInstituto de Humanidades, Artes e Ciências, Universidade Federal da Bahia, Salvador, Brazil.
Dulce FerrazFIOCRUZ Escola do Governo, Fundação Oswaldo Cruz, Brasília, Distrito Federal, Brazil.
Alexandre GrangeiroFaculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Marcelo CastellanosInstituto de Saúde Coletiva, Universidade Federal da Bahia, R. Basílio da Gama, s/n - Canela, Salvador, BA, CEP: 40110-040, Brazil.
Sandra Assis BrasilDepartmento de Ciências da Vida, Universidade Estadual da Bahia, Salvador, Brazil.
Inês DouradoInstituto de Saúde Coletiva, Universidade Federal da Bahia, R. Basílio da Gama, s/n - Canela, Salvador, BA, CEP: 40110-040, Brazil.
Universidade Federal da Bahia · BRFundação Oswaldo Cruz · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade Católica de Santos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescent men who have sex with men (aMSM) and transgender women (aTGW) are affected disproportionately by human immunodeficiency virus (HIV) infection. Although new methods of pre-exposure prophylaxis (PrEP), such as long-acting injectable (LAI-PrEP), have been approved by the Food and Drug Administration, their acceptability among aMSM/aTGW is not well known.

methodsForty-eight semi-structured interviews were conducted to assess the knowledge and interest in LAI-PrEP among aMSM/aTGW enrolled in a daily oral PrEP cohort from two capital cities of Brazil since 2019.

resultsPrevious knowledge of LAI-PrEP remains scarce, but the high interest regarding its use has been reported. Interest in the use of LAI-PrEP is associated with eliminating the burden of daily responsibility or the risk of missing the necessary medications, lowering the costs of this method, increasing confidentiality, and decreasing the frequency of visiting PrEP clinics. The reported barriers to uptake included fear of injection, doubts on its effectiveness, side effects, and greater dependence on a health provider.

conclusionsThere is an urgent need to strengthen the preventive strategies against HIV infection among the youth, enhance their knowledge and those of healthcare providers, and offer safe and new options.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesTransgender PersonsAdolescentBrazilCitiesFemaleHomosexuality, MaleHumansMalePatient Acceptance of Health CareAnti-HIV AgentsAcceptabilityAdolescentsHIV/AIDSLong-acting injectablePre-exposure prophylaxis

Identifiers

PMID36096758
PMCPMC9465661
OpenAlexW4295250078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.