Evidence map›Paper›PMID 36096642›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Identification of HLA-E Binding

Paula Ruibal, Kees L M C Franken, Krista E van Meijgaarden, Marjolein van Wolfswinkel, Ian Derksen, Ferenc A Scheeren, George M C Janssen, Peter A van Veelen, Charlotte Sarfas, Andrew D White and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Vaccines · 2024
    Article
  9. bioRxiv : the preprint server for biology · 2024
    Article
  10. Review
  11. iScience · 2024
    Article
  12. HLA-E/Frontiers in immunology · 2024
    Article
  13. MR1- and HLA-E-Dependent Antigen Presentation ofInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 4 countries.

Paula RuibalDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-3217-4497
Kees L M C FrankenDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Krista E van MeijgaardenDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-2818-9805
Marjolein van WolfswinkelDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-4952-9709
Ian DerksenDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
Ferenc A ScheerenDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0002-8304-9023
George M C JanssenCenter for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0001-9091-4030
Peter A van VeelenCenter for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0002-7898-9408
Charlotte SarfasResearch and Development Department, UK Health Security Agency, Salisbury, United Kingdom.ORCID 0000-0001-9056-0308
Andrew D WhiteResearch and Development Department, UK Health Security Agency, Salisbury, United Kingdom.ORCID 0000-0001-9481-0079
Sally A SharpeResearch and Development Department, UK Health Security Agency, Salisbury, United Kingdom.
Fabrizio PalmieriNational Institute for Infectious Diseases Lazzaro Spallanzani Scientific Institute for Research, Hospitalization and Healthcare, Rome, Italy.
Linda PetroneNational Institute for Infectious Diseases Lazzaro Spallanzani Scientific Institute for Research, Hospitalization and Healthcare, Rome, Italy.
Delia GolettiNational Institute for Infectious Diseases Lazzaro Spallanzani Scientific Institute for Research, Hospitalization and Healthcare, Rome, Italy.ORCID 0000-0001-8360-4376
Thomas AbeelDelft Bioinformatics Lab, Delft University of Technology, Delft, the Netherlands; and.ORCID 0000-0002-7205-7431
Tom H M OttenhoffDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-3706-3403
Simone A JoostenDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands; s.a.joosten@lumc.nl.ORCID 0000-0002-9878-0863
Leiden University Medical Center · NLEnvironment Agency · GBIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITBroad Institute · US

Funding

HLA-E restricted T-cell immunity in Mycobacterium tuberculosis infectionR01AI141315 · NIAID · LEIDEN UNIVERSITY MEDICAL CENTER · PI JOOSTEN, SIMONE ANNE · 2019 to 2022
$1.7M
In depth characterization of Mtb specific HLA-E restricted human CD8+ T-cellsR21AI127133 · NIAID · LEIDEN UNIVERSITY MEDICAL CENTER · PI OTTENHOFF, TOM · 2016 to 2017
$281k
NIAID NIH HHS R01 AI141315NIAID NIH HHS R21 AI127133
6 · The paper itself

Abstract

Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, posing great social and economic burden to affected countries. Novel vaccine approaches are needed to increase protective immunity against the causative agent

Indexed as

Mycobacterium tuberculosisTuberculosisAntigens, BacterialCD8-Positive T-LymphocytesEpitopes, T-LymphocyteHistocompatibility Antigens Class IHLA-E AntigensHumansPeptidesAntigens, BacterialEpitopes, T-LymphocyteHistocompatibility Antigens Class IHLA-E AntigensPeptides

Identifiers

PMID36096642
PMCPMC9536328
OpenAlexW4295441158

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.