Evidence map›Paper›PMID 36096408›Full record

ArticleThe American journal of tropical medicine and hygiene2022

Analysis of Zika Virus Sequence Data Associated with a School Cohort in Haiti.

Md Mahbubul Alam, Carla Mavian, Bernard A Okech, Sarah K White, Caroline J Stephenson, Maha A Elbadry, Gabriela M Blohm, Julia C Loeb, Rigan Louis, Cyrus Saleem and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Md Mahbubul AlamEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Carla MavianEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Bernard A OkechEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Sarah K WhiteEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Caroline J StephensonEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Maha A ElbadryEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Gabriela M BlohmEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Julia C LoebEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Rigan LouisEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Cyrus SaleemEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Valery E Madsen Beau de RocharsEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Marco SalemiEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
John A LednickyEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
J Glenn MorrisEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
University of Florida · US

Funding

Recurrence of Cholera in Haiti: Exploration of Contributing Factors and Intervention StrategiesR01AI126357 · NIAID · UNIVERSITY OF FLORIDA · PI John Glenn Morris · 2016 to 2026
$7.3M
NIAID NIH HHS R01 AI126357
6 · The paper itself

Abstract

Zika virus (ZIKV) infections occurred in epidemic form in the Americas in 2014-2016, with some of the earliest isolates in the region coming from Haiti. We isolated ZIKV from 20 children with acute undifferentiated febrile illness who were part of a cohort of children seen at a school clinic in the Gressier region of Haiti. The virus was also isolated from three pools of Aedes aegypti mosquitoes collected at the same location. On phylogenetic analysis, three distinct ZIKV clades were identified. Strains from all three clades were present in Haiti in 2014, making them among the earliest isolates identified in the Western Hemisphere. Strains from all three clades were also isolated in 2016, indicative of their persistence across the time period of the epidemic. Mosquito isolates were collected in 2016 and included representatives from two of the three clades; in one instance, ZIKV was isolated from a pool of male mosquitoes, suggestive of vertical transmission of the virus. The identification of multiple ZIKV clades in Haiti at the beginning of the epidemic suggests that Haiti served as a nidus for transmission within the Caribbean.

Indexed as

AedesZika VirusZika Virus InfectionAnimalsChildHaitiHumansMaleMosquito VectorsPhylogenySchools

Identifiers

PMID36096408
PMCPMC9651511
OpenAlexW4295280085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.