Evidence map›Paper›PMID 36096406›Full record

ArticleThe American journal of tropical medicine and hygiene2022

COVID-19 Vaccine Effectiveness during a Prison Outbreak when Omicron was the Dominant Circulating Variant-Zambia, December 2021.

John Simwanza, Jonas Z Hines, Danny Sinyange, Nyambe Sinyange, Chilufya Mulenga, Sarah Hanyinza, Patrick Sakubita, Nelia Langa, Haggai Nowa, Priscilla Gardner and 16 more

Open access · hybridAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 5 institutions in 1 country.

John SimwanzaZambia Field Epidemiology Training Programme, Lusaka, Zambia.
Jonas Z HinesCenters for Disease Control and Prevention, Lusaka, Zambia.
Danny SinyangeZambia Field Epidemiology Training Programme, Lusaka, Zambia.
Nyambe SinyangeZambia National Public Health Institute, Lusaka, Zambia.
Chilufya MulengaZambia Field Epidemiology Training Programme, Lusaka, Zambia.
Sarah HanyinzaZambia National Public Health Institute, Lusaka, Zambia.
Patrick SakubitaZambia National Public Health Institute, Lusaka, Zambia.
Nelia LangaZambia National Public Health Institute, Lusaka, Zambia.
Haggai NowaZambia Correctional Services, Lusaka, Zambia.
Priscilla GardnerLusaka Province Health Office, Lusaka, Zambia.
Ngonda SaasaUniversity of Zambia, School of Veterinary Medicine, Department of Disease Control, Lusaka, Zambia.
Graham ChitempaLusaka District Health Office, Lusaka, Zambia.
James SimpungweCenters for Disease Control and Prevention, Lusaka, Zambia.
Warren MalamboCenters for Disease Control and Prevention, Lusaka, Zambia.
Busiku HamainzaNational Malaria Elimination Centre, Lusaka, Zambia.
Peter J ChipimoZambia National Public Health Institute, Lusaka, Zambia.
Nathan KapataZambia National Public Health Institute, Lusaka, Zambia.
Muzala KapinaZambia National Public Health Institute, Lusaka, Zambia.
Kunda MusondaZambia National Public Health Institute, Lusaka, Zambia.
Mazyanga LiweweZambia National Public Health Institute, Lusaka, Zambia.
Consity MwaleLusaka Province Health Office, Lusaka, Zambia.
Sombo FwoloshiMinistry of Health, Lusaka, Zambia.
Lloyd B MulengaMinistry of Health, Lusaka, Zambia.
Simon AgoloryCenters for Disease Control and Prevention, Lusaka, Zambia.
Victor MukonkaZambia National Public Health Institute, Lusaka, Zambia.
Roma ChilengiZambia National Public Health Institute, Lusaka, Zambia.
Zambia National Public Health Institute · ZMCentre for Infectious Disease Research in Zambia · ZMMinistry of Health · ZMNational HIV/AIDS/STI/TB Council · ZMUniversity of Zambia · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During a COVID-19 outbreak in a prison in Zambia from December 14 to 19, 2021, a case-control study was done to measure vaccine effectiveness (VE) against infection and symptomatic infection, when the Omicron variant was the dominant circulating variant. Among 382 participants, 74.1% were fully vaccinated, and the median time since full vaccination was 54 days. There were no hospitalizations or deaths. COVID-19 VE against any SARS-CoV-2 infection was 64.8%, and VE against symptomatic SARS-CoV-2 infection was 72.9%. COVID-19 vaccination helped protect incarcerated persons against SARS-CoV-2 infection during an outbreak while Omicron was the dominant variant in Zambia. These findings provide important local evidence that might be used to increase COVID-19 vaccination in Zambia and other countries in Africa.

Indexed as

COVID-19COVID-19 VaccinesCase-Control StudiesDisease OutbreaksHumansPrisonsSARS-CoV-2Vaccine EfficacyZambiaCOVID-19 Vaccines

Identifiers

PMID36096406
PMCPMC9709003
OpenAlexW4295280073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.