Evidence map›Paper›PMID 36096085›Full record

ArticleInternational journal of surgery case reports2022

Paroxysmal sympathetic hyperactivity syndrome in tuberculous meningitis with paradoxical reaction.

Andre Marolop Pangihutan Siahaan, Steven Tandean, Rr Suzy Indharty, Bahagia Willibrodus Maria Nainggolan, Martin Susanto

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Paroxysmal sympathetic hyperactivity in tubercular meningitis: An underacknowledged association.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Andre Marolop Pangihutan SiahaanDepartment of Neurosurgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia. Electronic address: andremarolop@usu.ac.id.
Steven TandeanDepartment of Neurosurgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Rr Suzy IndhartyDepartment of Neurosurgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Bahagia Willibrodus Maria NainggolanStudent Research Assistant, Department of Neurosurgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Martin SusantoPetang II Public Health Center, Bali, Indonesia.
University of North Sumatra · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and importanceParoxysmal sympathetic hyperactivity syndrome is frequently reported in traumatic brain injury. However, it may occur in non-traumatic brain injury, such as tuberculous meningitis with hydrocephalus. CASE PRESENTATION: We reported a 38-year-old male who presented with acute decrease of consciousness and hemiparesis that was developed during antitubercular drugs therapy. CT Scan showed hydrocephalus and granuloma lesion. Emergency ventriculoperitoneal shunting were performed. During treatment, the patient developed paroxysmal sympathetic syndrome during treatment that was controlled based on symptom elimination and prevention. CLINICAL DISCUSSION: Brain tuberculosis remains a difficult problem for clinicians. Even when antitubercular drugs are administered according to protocol, paradoxical reactions can occur. If hydrocephalus develops, ventriculoperitoneal shunting is one of the options for lowering intracranial pressure. Paroxysmal sympathetic hyperactivity may occur in brain tuberculosis and should be detected as soon as possible to avoid serious morbidity.

conclusionParoxysmal sympathetic hyperactivity may be developed in brain tuberculosis. Early identification and treatment are mandatory.

Indexed as

Case reportParadoxical reactionParoxysmal sympathetic hyperactivityTuberculous meningitis

Identifiers

PMID36096085
PMCPMC9568713
OpenAlexW4295480316

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.