Evidence map›Paper›PMID 36095217›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Active forgetting requires Sickie function in a dedicated dopamine circuit in

Xiaofan Zhang, John Martin Sabandal, George Tsaprailis, Ronald L Davis

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Dynamics of two distinct memory interactions during water seeking inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Genetics and Molecular Biology of Memory Suppression.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  6. Review
  7. Article
  8. Active forgetting requires Sickie function in a dedicated dopamine circuit inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaofan ZhangDepartment of Neuroscience, Scripps Research Institute Florida, Jupiter, FL 33458.
John Martin SabandalDepartment of Neuroscience, Scripps Research Institute Florida, Jupiter, FL 33458.
George TsaprailisProteomics Core, UF Scripps Biomedical, Jupiter, FL 33458.ORCID 0000-0003-1239-2358
Ronald L DavisDepartment of Neuroscience, Scripps Research Institute Florida, Jupiter, FL 33458.

Funding

Biology of memoryR35NS097224 · NINDS · UNIVERSITY OF FLORIDA · PI DAVIS, RONALD L · 2017 to 2024
$9.1M
Molecular Biology of Drosophila Learning and MemoryR37NS019904 · NINDS · SCRIPPS FLORIDA · PI DAVIS, RONALD L · 2013 to 2016
$1.9M
NINDS NIH HHS R35 NS097224NINDS NIH HHS R37 NS019904
6 · The paper itself

Abstract

Forgetting is an essential component of the brain's memory management system, providing a balance to memory formation processes by removing unused or unwanted memories, or by suppressing their expression. However, the molecular, cellular, and circuit mechanisms underlying forgetting are poorly understood. Here we show that the memory suppressor gene,

Indexed as

DopamineDrosophila melanogasterDrosophila ProteinsMemoryNerve Tissue ProteinsAnimalsPresynaptic TerminalsSynaptic TransmissionDopamineDrosophila ProteinsNerve Tissue Proteinssick protein, Drosophilaactive forgettingBruchpilotdopamineDrosophilaSickie

Identifiers

PMID36095217
PMCPMC9499536

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.