Evidence map›Paper›PMID 36095210›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Real-time imaging of

Pablo J Lituma, Robert H Singer, Sulagna Das, Pablo E Castillo

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pablo J LitumaDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461.
Robert H SingerDepartment of Cell Biology, Albert Einstein College of Medicine, New York, NY 10461.ORCID 0000-0002-6725-0093
Sulagna DasDepartment of Cell Biology, Albert Einstein College of Medicine, New York, NY 10461.
Pablo E CastilloDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461.ORCID 0000-0002-9834-1801
Albert Einstein College of Medicine · US

Funding

Mechanism of MRNA Localization and Localized Translation in NeuronsR01NS083085 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Sulagna Das, Robert H Singer · 2013 to 2026
$9.0M
SUPPORT FOR THE ROSE F KENNEDY IDDRC P50P50HD105352 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SOPHIE MOLHOLM, Steven Upshaw Walkley · 2021 to 2026
$7.0M
Presynaptic forms of long-term plasticity in the CNSR01MH125772 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI PABLO E CASTILLO · 2020 to 2026
$3.6M
Synaptic Mechanisms for Contextual Memory FormationR01MH116673 · NIMH · UPSTATE MEDICAL UNIVERSITY · PI CASTILLO, PABLO E, LIN, YINGXI · 2019 to 2023
$3.4M
Activity-Dependent Plasticity in an Associative Hippocampal Circuit: Mechanisms, Synaptic Learning Rules and Involvement in DiseaseR01NS113600 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CASTILLO, PABLO E · 2019 to 2023
$2.7M
Temporal dynamics of Arc (Arg3.1) transcriptional regulationR21MH122961 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DAS, SULAGNA · 2021 to 2022
$462k
Presynaptic NMDAR Function in the HippocampusF31MH109267 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LITUMA, PABLO · 2015 to 2019
$174k
NICHD NIH HHS P50 HD105352NIMH NIH HHS F31 MH109267NIMH NIH HHS R01 MH116673NIMH NIH HHS R01 MH125772NIMH NIH HHS R21 MH122961NINDS NIH HHS R01 NS083085NINDS NIH HHS R01 NS113600
6 · The paper itself

Abstract

The ability of neurons to process and store salient environmental features underlies information processing in the brain. Long-term information storage requires synaptic plasticity and regulation of gene expression. While distinct patterns of activity have been linked to synaptic plasticity, their impact on immediate early gene (IEG) expression remains poorly understood. The activity regulated cytoskeleton associated (

Indexed as

Cytoskeletal ProteinsGenes, Immediate-EarlyNerve Tissue ProteinsNeuronal PlasticityTranscription, GeneticAnimalsMiceSynapsesactivity regulated cytoskeletal-associated proteinCytoskeletal ProteinsNerve Tissue Proteinsendoplasmic reticulumimmediate early geneinput specificityreal-time imagingtranscription

Identifiers

PMID36095210
PMCPMC9499544
OpenAlexW4295308901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.