Evidence map›Paper›PMID 36095204›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Layer 5 of cortex innervates the thalamic reticular nucleus in mice.

Briana J Carroll, Vandana Sampathkumar, Narayanan Kasthuri, S Murray Sherman

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
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  4. Temporally Coordinated Activity among Motor Cortex, Thalamus, and Thalamic Reticular Nucleus Neurons during Rat Forelimb Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Article
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  11. Transthalamic Pathways for Cortical Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  12. Thalamocortical mGlu8 Modulates Dorsal Thalamus Excitatory Transmission and Sensorimotor Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  13. Article
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  15. Review
  16. Article
  17. Layer 5 of cortex innervates the thalamic reticular nucleus in mice.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Briana J CarrollDepartment of Neurobiology, The University of Chicago, Chicago, IL 60637.
Vandana SampathkumarDepartment of Neurobiology, The University of Chicago, Chicago, IL 60637.ORCID 0000-0002-0577-7164
Narayanan KasthuriDepartment of Neurobiology, The University of Chicago, Chicago, IL 60637.
S Murray ShermanDepartment of Neurobiology, The University of Chicago, Chicago, IL 60637.ORCID 0000-0002-1520-2778
Argonne National Laboratory · USUniversity of Chicago · US

Funding

Thalamocortical interactionsR01NS094184 · NINDS · UNIVERSITY OF CHICAGO · PI Jason Neil MacLean, S. Murray SHERMAN · 2016 to 2026
$4.6M
Connectome of circuits within and between thalamus and cortexR01NS113922 · NINDS · UNIVERSITY OF CHICAGO · PI KASTHURI, NARAYANAN, SHERMAN, S. MURRAY · 2020 to 2024
$2.8M
NINDS NIH HHS R01 NS094184NINDS NIH HHS R01 NS113922
6 · The paper itself

Abstract

Neurons in the thalamic reticular nucleus (TRN) are a primary source of inhibition to the dorsal thalamus and, as they are innervated in part by the cortex, are a means of corticothalamic regulation. Previously, cortical inputs to the TRN were thought to originate solely from layer 6 (L6), but we recently reported the presence of putative synaptic terminals from layer 5 (L5) neurons in multiple cortical areas in the TRN [J. A. Prasad, B. J. Carroll, S. M. Sherman,

Indexed as

Cerebral CortexVentral Thalamic NucleiAnimalsMiceMicroscopy, ElectronNeural InhibitionNeuronsPresynaptic Terminalscorticothalamiclayer 5thalamic reticular nucleus

Identifiers

PMID36095204
PMCPMC9499584
OpenAlexW4295308958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.