Evidence map›Paper›PMID 36095096›Full record

ArticleAutophagy2023

Apicoplast biogenesis mediated by ATG8 requires the ATG12-ATG5-ATG16L and SNAP29 complexes in

Jiawen Fu, Lin Zhao, Yu Pang, Heming Chen, Hayashi Yamamoto, Yuntong Chen, Zhaoran Li, Noboru Mizushima, Honglin Jia

Open access · greenAbstract read
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. bioRxiv : the preprint server for biology · 2026
    Article
  6. The Roles of SQSTM1/p62 in Selective Autophagy and Oncogenic Signaling.International journal of molecular sciences · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. mSphere · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Autophagy genes in biology and disease.Nature reviews. Genetics · 2023
    Review
  17. Article
  18. Article
  19. Regulation of phosphoinositide metabolism in Apicomplexan parasites.Frontiers in cell and developmental biology · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jiawen FuState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, HeilongjiangChina.
Lin ZhaoState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, HeilongjiangChina.
Yu PangState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, HeilongjiangChina.
Heming ChenState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, HeilongjiangChina.
Hayashi YamamotoDepartment of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yuntong ChenState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, HeilongjiangChina.
Zhaoran LiState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, HeilongjiangChina.
Noboru MizushimaDepartment of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-6258-6444
Honglin JiaState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, HeilongjiangChina.ORCID 0000-0001-7458-9565
Chinese Academy of Agricultural Sciences · CNThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In apicomplexan parasites, the macroautophagy/autophagy machinery is repurposed to maintain the plastid-like organelle apicoplast. Previously, we showed that in

Indexed as

ApicoplastsParasitesToxoplasmaAnimalsAutophagyAutophagy-Related Protein 12Autophagy-Related Protein 5EthylmaleimideHumansProtozoan ProteinsQb-SNARE ProteinsQc-SNARE ProteinsUbiquitinsATG12 protein, humanATG5 protein, humanAutophagy-Related Protein 12Autophagy-Related Protein 5EthylmaleimideProtozoan ProteinsQb-SNARE ProteinsQc-SNARE ProteinsSNAP29 protein, humanUbiquitinsApicoplastTgATG12–TgATG5-TgATG16LTgATG8T. gondiiTgSNAP29ubiquitin-interacting motif

Identifiers

PMID36095096
PMCPMC10012919
OpenAlexW4295517603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.