Evidence map›Paper›PMID 36094754›Full record

ReviewStem cell reviews and reports2023

METTLing in Stem Cell and Cancer Biology.

John G Tooley, James P Catlin, Christine E Schaner Tooley

Open access · greenAbstract readReview
In one paragraph

Review in Stem cell reviews and reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Subtype-Specific mInternational journal of molecular sciences · 2026
    Article
  8. Article
  9. The Emerging Role of METTL3 in Lung Diseases.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Identification of mDiscover oncology · 2025
    Article
  15. Article
  16. Article
  17. METTL5 in physiology and pathology: mechanisms and implications.Frontiers in cell and developmental biology · 2025
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John G TooleyDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 955 Main St., Buffalo, NY, 14203, USA.
James P CatlinDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 955 Main St., Buffalo, NY, 14203, USA.
Christine E Schaner TooleyDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 955 Main St., Buffalo, NY, 14203, USA. ceschane@buffalo.edu.ORCID 0000-0001-9133-5583
University at Buffalo, State University of New York · US

Funding

Regulation of NRMT1 through homolog bindingR35GM144111 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Christine E Schaner-Tooley · 2022 to 2026
$2.1M
NIGMS NIH HHS R35 GM144111
6 · The paper itself

Abstract

The methyltransferase-like (METTL) family is a diverse group of methyltransferases that can methylate nucleotides, proteins, and small molecules. Despite this diverse array of substrates, they all share a characteristic seven-beta-strand catalytic domain, and recent evidence suggests many also share an important role in stem cell biology. The most well characterized family members METTL3 and METTL14 dimerize to form an N

Indexed as

MethyltransferasesNeoplasmsAnimalsBiologyCell DifferentiationEmbryonic Stem CellsMiceRNAMethyltransferasesRNACancerMetabolismMethyltransferaseMETTLStem cellTranscriptionTranslation

Identifiers

PMID36094754
PMCPMC10563446
OpenAlexW4296527790

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.