Evidence map›Paper›PMID 36094451›Full record

Trial reportAmerican journal of physiology. Regulatory, integrative and comparative physiology2022

Influence of graded hypercapnia on endurance exercise performance in healthy humans.

Benjamin J Ryan, Afton D Seeley, Dina M Pitsas, Thomas A Mayer, Aaron R Caldwell, Tyrone G Ceaser, Adam J Luippold, Nisha Charkoudian, Roy M Salgado

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of physiology. Regulatory, integrative and comparative physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Review
  3. EEG-Metabolic Coupling and Time Limit at V˙OJournal of functional morphology and kinesiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Benjamin J RyanThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.ORCID 0000-0001-5848-6988
Afton D SeeleyThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.ORCID 0000-0002-3514-1423
Dina M PitsasThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.
Thomas A MayerThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.
Aaron R CaldwellThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.ORCID 0000-0002-4541-6283
Tyrone G CeaserThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.
Adam J LuippoldThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.
Nisha CharkoudianThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.ORCID 0000-0002-4958-5279
Roy M SalgadoThermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts.ORCID 0000-0002-4306-4130
U.S. Army Research Institute of Environmental Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Military and/or emergency services personnel may be required to perform high-intensity physical activity during exposure to elevated inspired carbon dioxide (CO

Indexed as

Carbon DioxideHypercapniaExercise TestFemaleHumansOxygenOxygen ConsumptionPhysical EnduranceSingle-Blind MethodCarbon DioxideOxygencarbon dioxideenvironmental stresshypercarbiarespiratory acidosis

Identifiers

PMID36094451
PMCPMC9602925
OpenAlexW4296553248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.