Evidence map›Paper›PMID 36094445›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2022

Altered skeletal muscle sarco-endoplasmic reticulum Ca

Lydia A Heemstra, Lauren G Koch, Steven L Britton, Colleen M Novak

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lydia A HeemstraDepartment of Biological Sciences, Kent State University, Kent, Ohio.
Lauren G KochDepartment of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.ORCID 0000-0002-2019-5939
Steven L BrittonDepartment of Anesthesiology, University of Michigan, Ann Arbor, Michigan.
Colleen M NovakDepartment of Biological Sciences, Kent State University, Kent, Ohio.ORCID 0000-0002-8542-1677
Kent State University · USUniversity of Michigan · USUniversity of Toledo · US

Funding

Resource for Rat Genetic Models of Aerobic CapacityP40OD021331 · OD · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI KOCH, LAUREN GERARD · 2015 to 2019
$1.9M
Neural Mechanisms Underlying Central Induction of Skeletal Muscle ThermogenesisR15DK121246 · NIDDK · KENT STATE UNIVERSITY · PI NOVAK, COLLEEN M · 2020 to 2024
$906k
NIDDK NIH HHS R15 DK121246NIH HHS P40 OD021331
6 · The paper itself

Abstract

Exposure to predator threat induces a rapid and robust increase in skeletal muscle thermogenesis in rats. The central nervous system relays threat information to skeletal muscle through activation of the sympathetic nervous system, but muscle mechanisms mediating this thermogenesis remain unidentified. Given the relevance of sarcolipin-mediated futile calcium cycling through the sarco-endoplasmic reticulum Ca

Indexed as

CalciumSarcoplasmic Reticulum Calcium-Transporting ATPasesAdenosine TriphosphateAnimalsFerretsMuscle, SkeletalRatsRats, Sprague-DawleySarcoplasmic ReticulumThermogenesisAdenosine TriphosphateCalciumSarcoplasmic Reticulum Calcium-Transporting ATPasesaerobic fitnessfutile calcium cyclingobesitysarcolipinstress-induced hyperthermia

Identifiers

PMID36094445
PMCPMC9602703
OpenAlexW4296553862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.