Evidence map›Paper›PMID 36094205›Full record

ArticleAntimicrobial agents and chemotherapy2022

Drug Repurposing for Therapeutic Discovery against Human Metapneumovirus Infection.

Annelies Van Den Bergh, Patrice Guillon, Mark von Itzstein, Benjamin Bailly, Larissa Dirr

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Annelies Van Den BerghInstitute for Glycomics, Griffith University, Gold Coast Campus, Queensland, Australia.ORCID 0000-0002-2873-7608
Patrice GuillonInstitute for Glycomics, Griffith University, Gold Coast Campus, Queensland, Australia.ORCID 0000-0002-9639-183X
Mark von ItzsteinInstitute for Glycomics, Griffith University, Gold Coast Campus, Queensland, Australia.ORCID 0000-0001-6302-7524
Benjamin BaillyInstitute for Glycomics, Griffith University, Gold Coast Campus, Queensland, Australia.ORCID 0000-0003-0782-2325
Larissa DirrInstitute for Glycomics, Griffith University, Gold Coast Campus, Queensland, Australia.ORCID 0000-0002-5794-266X
Griffith University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human metapneumovirus (HMPV) is recognized as an important cause of pneumonia in infants, in the elderly, and in immunocompromised individuals worldwide. The absence of an antiviral treatment or vaccine strategy against HMPV infection creates a high burden on the global health care system. Drug repurposing has become increasingly attractive for the treatment of emerging and endemic diseases as it requires less research and development costs than traditional drug discovery. In this study, we developed an

Indexed as

MetapneumovirusParamyxoviridae InfectionsAgedAntiviral AgentsAurintricarboxylic AcidDrug RepositioningEvans BlueGuanosineHumansInfantMycophenolic AcidAntiviral AgentsAurintricarboxylic AcidEvans BlueGuanosineMycophenolic Acidantiviralantiviral drug repurposingapproved drugsdrug repurposinghuman metapneumovirusmedium-throughput screeningmode of action

Identifiers

PMID36094205
PMCPMC9578393
OpenAlexW4295886642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.