Evidence map›Paper›PMID 36094085›Full record

ArticleMicrobiology spectrum2022

Boid Inclusion Body Disease Is Also a Disease of Wild Boa Constrictors.

Alejandro Alfaro-Alarcón, Udo Hetzel, Teemu Smura, Francesca Baggio, Juan Alberto Morales, Anja Kipar, Jussi Hepojoki

Open access · goldAbstract read
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Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Alejandro Alfaro-Alarcón *Departamento de Patología, Escuela de Medicina Veterinaria, Universidad Nacional, Heredia, Costa Rica.
Udo Hetzel *Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurichgrid.7400.3, Zurich, Switzerland.
Teemu SmuraUniversity of Helsinkigrid.7737.4, Faculty of Medicine, Medicum, Department of Virology, Helsinki, Finland.
Francesca BaggioInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurichgrid.7400.3, Zurich, Switzerland.
Juan Alberto MoralesDepartamento de Patología, Escuela de Medicina Veterinaria, Universidad Nacional, Heredia, Costa Rica.
Anja KiparInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurichgrid.7400.3, Zurich, Switzerland.ORCID 0000-0001-7289-3459
Jussi HepojokiInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurichgrid.7400.3, Zurich, Switzerland.ORCID 0000-0001-5699-214X
University of Helsinki · FIUniversidad Nacional · CRUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reptarenaviruses cause boid inclusion body disease (BIBD), a potentially fatal disease, occurring in captive constrictor snakes boas and pythons worldwide. Classical BIBD, characterized by the formation of pathognomonic cytoplasmic inclusion bodies (IBs), occurs mainly in boas, whereas in pythons, for example, reptarenavirus infection most often manifests as central nervous system signs with limited IB formation. The natural hosts of reptarenaviruses are unknown, although free-ranging/wild constrictor snakes are among the suspects. Here, we report BIBD with reptarenavirus infection in indigenous captive and wild boid snakes in Costa Rica using histology, immunohistology, transmission electron microscopy, and next-generation sequencing (NGS). The snakes studied represented diagnostic postmortem cases of captive and wild-caught snakes since 1989. The results from NGS on archival paraffin blocks confirm that reptarenaviruses were already present in wild boa constrictors in Costa Rica in the 1980s. Continuous sequences that were

Indexed as

ArenaviridaeArenaviridae InfectionsBoidaeCommunicable DiseasesAnimalsInclusion BodiesParaffinRNAParaffinRNAarenavirusboa constrictorboid inclusion body diseaseinclusion body diseaseveterinary microbiologyviral pathogenesiswild snake

Identifiers

PMID36094085
PMCPMC9602588
OpenAlexW4295292789

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.