ArticleJournal of extracellular vesicles2022
An immunogold single extracellular vesicular RNA and protein (
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Article in Journal of extracellular vesicles, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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0cells of the map it votes in
31citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
What it found
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Who cites it
31 citing papers in PubMed, 51 citations in OpenAlex.
- Markers and Enrichment Strategies for Brain-Derived Extracellular Vesicles: Current Evidence, Limitations and Future Directions.Neuromolecular medicine · 2026Review
- Revisiting the Abscopal Effect in the Era of Immuno-Radiotherapy: Mechanisms, Challenges, and Clinical Perspectives.Biomolecules · 2026Review
- Multidimensional Cellular Micro-Compartments to Model Invasive Lobular Carcinoma Dormancy.Advanced healthcare materials · 2026Article
- High-throughput single-vesicle imaging platform for direct extracellular vesicle profiling of human plasma.Nature communications · 2026Article
- Microsystem technologies for accelerating the discovery and translation of immunotherapies.Nature reviews. Drug discovery · 2026Review
- Unveiling Heterogeneity: Innovations and Challenges in Single-Vesicle Analysis for Clinical Translation.Journal of extracellular vesicles · 2025Article
- Light-induced extracellular vesicle and particle adsorption.Nature methods · 2025Article
- Signal Amplification for Fluorescent Staining of Single Particles in Liquid Biopsies: Circulating Tumour Cells and Extracellular Vesicles.Journal of extracellular vesicles · 2025Article
- Extracellular Vesicles for Clinical Diagnostics: From Bulk Measurements to Single-Vesicle Analysis.ACS nano · 2025Review
- Extracellular vesicles as biomarkers and drug delivery systems for tumor.Acta pharmaceutica Sinica. B · 2025Review
- Extracellular Vesicular Delta-Like Ligand 3 and Subtype Transcription Factors for Small Cell Lung Cancer Diagnosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
- [Progress and prospect of separation and analysis of single-cell and single-particle exosomes].Se pu = Chinese journal of chromatography · 2025Review
- Nanotechnology-driven platforms for extracellular vesicle analysis in tumor immunotherapy.Frontiers in immunology · 2025Review
- Integrated Antigenic and Nucleic Acid Detection in Single Virions and Extracellular Vesicles with Viral Content.Advanced healthcare materials · 2025Article
- Recent advances in biomarkers for predicting the efficacy of immunotherapy in non-small cell lung cancer.Frontiers in immunology · 2025Review
- Extracellular RNA communication: A decade of NIH common fund support illuminates exRNA biology.Journal of extracellular vesicles · 2025Review
- Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles.Journal of controlled release : official journal of the Controlled Release Society · 2024Article
- Portable Aptasensor Based on Parallel Rolling Circle Amplification for Tumor-Derived Exosomes Liquid Biopsy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Current status and progress of PD-L1 detection: guiding immunotherapy for non-small cell lung cancer.Clinical and experimental medicine · 2024Review
Corrections and comments
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Authors and funding
18 authors at 2 institutions in 2 countries.
Luong T H NguyenWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Jingjing ZhangWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Xilal Y RimaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Xinyu WangWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Kwang Joo KwakSpot Biosystems Ltd., Palo Alto, California, USA.
Tamio OkimotoComprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Joseph AmannComprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Min Jin YoonWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Takehito ShukuyaComprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Chi-Ling ChiangWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Nicole WaltersWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Yifan MaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Donald BelcherWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Hong LiWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Andre F PalmerWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
David P CarboneComprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
L James LeeWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
Eduardo ReáteguiWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio, State University, Columbus, Ohio, USA.
The Ohio State University · USSystem Biosciences (United States) · US
Funding
Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3MECOG-ACRIN Thoracic Malignancies Integrated Translational Science CenterUG1CA233259 · NCI · EMORY UNIVERSITY · PI CARBONE, DAVID P., LEAL, TICIANA · 2019 to 2025
$5.1MPEGylated megahemoglobin for use as a red blood cell substituteR01HL138116 · NHLBI · OHIO STATE UNIVERSITY · PI CABRALES, PEDRO, KAUMAYA, PRAVIN T. P. · 2017 to 2020
$2.9MFractionation of Aged RBCs Based on Hemoglobin ContentR01HL131720 · NHLBI · OHIO STATE UNIVERSITY · PI CHALMERS, JEFFREY JOHN, PALMER, ANDRE FRANCIS · 2017 to 2020
$2.7MMulti-parametric Integrated Molecular Detection of SARS-CoV-2 from Biofluids by Adapting Single Extracellular Vesicle Characterization TechnologiesU18TR003807 · NCATS · OHIO STATE UNIVERSITY · PI LEE, INYOUL, LEE, LY JAMES · 2021 to 2022
$1.8MAttenuating the Oxidative and Myocardial Side-Effects of Acellular HemoglobinR01HL126945 · NHLBI · OHIO STATE UNIVERSITY · PI CABRALES, PEDRO, PALMER, ANDRE FRANCIS · 2016 to 2019
$1.7MPolymerized Hemoglobins for Facilitated Oxygen Transport in Hepatic BioreactorsR01EB021926 · NIBIB · OHIO STATE UNIVERSITY · PI BERTHIAUME, FRANCOIS, PALMER, ANDRE FRANCIS · 2016 to 2019
$1.4MMicrofluidics Array Based Sorting, Isolation, and RNA Analysis in Single Extracellular V csiclesUG3TR002884 · NCATS · OHIO STATE UNIVERSITY · PI KIM, BETTY, REATEGUI, EDUARDO · 2019 to 2020
$822kNCATS NIH HHS U18 TR003807NCATS NIH HHS UG3 TR002884NCI NIH HHS P30 CA016058NCI NIH HHS UG1 CA233259NHLBI NIH HHS R01 HL126945NHLBI NIH HHS R01 HL131720NHLBI NIH HHS R01 HL138116NIBIB NIH HHS R01 EB021926
Abstract
Conventional PD-L1 immunohistochemical tissue biopsies only predict 20%-40% of non-small cell lung cancer (NSCLC) patients that will respond positively to anti-PD-1/PD-L1 immunotherapy. Herein, we present an immunogold biochip to quantify single extracellular vesicular RNA and protein (
Indexed as
Carcinoma, Non-Small-Cell LungExtracellular VesiclesLung NeoplasmsB7-H1 AntigenBiomarkersHumansImmunologic FactorsImmunotherapyRNARNA, MessengerB7-H1 AntigenBiomarkersImmunologic FactorsRNARNA, Messenger
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What OpenQuestion holds
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.