Evidence map›Paper›PMID 36093430›Full record

ArticleTalanta open2022

Fabrication of paper-based microfluidic devices using a 3D printer and a commercially-available wax filament.

Antonio Espinosa, Joannes Diaz, Edgar Vazquez, Lina Acosta, Arianna Santiago, Lisandro Cunci

Abstract read
In one paragraph

Article in Talanta open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonio EspinosaDepartment of Chemistry, Universidad Ana G. Méndez - Recinto de Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Joannes DiazDepartment of Chemistry, Universidad Ana G. Méndez - Recinto de Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Edgar VazquezDepartment of Chemistry, Universidad Ana G. Méndez - Recinto de Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Lina AcostaDepartment of Chemistry, Universidad Ana G. Méndez - Recinto de Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Arianna SantiagoDepartment of Chemistry, Universidad Ana G. Méndez - Recinto de Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Lisandro CunciDepartment of Chemistry, Universidad Ana G. Méndez - Recinto de Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.

Funding

SCIENCE AND TECHNOLOGY COMPETENCY & EDUCATION CORE (STCE)P20GM103475 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Jose R. Rodriguez-Medina · 2012 to 2026
$52.9M
Development and Validation of an NPY-sensitive Microelectrode for Measuring NPY Release from HippocampusR21MH129037 · NIMH · UNIVERSITY COLLEGE OF TURABO (CAGUAS,PR) · PI CUNCI, LISANDRO, DOBRUNZ, LYNN E · 2021 to 2022
$382k
NIGMS NIH HHS P20 GM103475NIMH NIH HHS R21 MH129037
6 · The paper itself

Abstract

In this work, we developed an alternative manufacturing paper-based microfluidics method through 3D printing and wax filament. Microfluidic paper-based analytical devices (μPADs) are low-cost and easy-to-manufacture tools used for various chemical and biological analyses and studies. Paper-based microfluidics with wax has been limited as the manufacturers have discontinued most wax printing equipment. We aim to develop a low-cost and accessible manufacturing method that can replace conventional wax-on paper-based microfluidic manufacturing methods. Using highly available commercial 3D printing technology and wax filament, we could create hydrophobic wax barriers on the surface of different paper types. The properties and limits of this manufacturing method were characterized. Moreover, using this paper-based microfluidic manufacturing method, we were able to measure dopamine electrochemically using μPAD as a passive flow-based method in concentrations as low as 1 nM using injections as small as 15 μL.

Indexed as

3D printerMicrofluidic paper-based analytical devicesPassive flowWax filament

Identifiers

PMID36093430
PMCPMC9454060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.