Evidence map›Paper›PMID 36093391›Full record

ArticleFrontiers in pain research (Lausanne, Switzerland)2022

National prevalence of IC/BPS in women and men utilizing veterans health administration data.

Jennifer T Anger, Kai B Dallas, Catherine Bresee, Amanda M De Hoedt, Kamil E Barbour, Katherine J Hoggatt, Marc T Goodman, Jayoung Kim, Stephen J Freedland

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pain research (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
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  7. Interstitial Cystitis/Bladder Pain Syndrome in Men.Neurourology and urodynamics · 2026
    Review
  8. Review
  9. Review
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  11. 2025 Canadian Urological Association Guideline: Selected treatment recommendations for interstitial cystitis/bladder pain syndrome.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  12. Review
  13. Review
  14. Article
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  16. Article
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  19. Interstitial cystitis-an imbalance of risk and protective factors?Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jennifer T AngerDepartment of Urology, UC San Diego Health, San Diego, CA, United States.
Kai B DallasCity of Hope Urology, Duarte, CA, United States.
Catherine BreseeDepartment of Biostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Amanda M De HoedtUrology Section, Department of Surgery, Veterans Affairs Medical Centers Division of Population Health, Durham, NC, United States.
Kamil E BarbourNational Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Katherine J HoggattCenter for Study of Healthcare Implementation, Innovation and Policy Veterans Health Administration, Los Angeles, CA, United States.
Marc T GoodmanCedars-Sinai Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Jayoung KimCedars-Sinai Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Stephen J FreedlandUrology Section, Department of Surgery, Veterans Affairs Medical Centers Division of Population Health, Durham, NC, United States.
Cedars-Sinai Medical Center · USVeterans Health Administration · USCity of Hope · USNational Center for Chronic Disease Prevention and Health Promotion · USUC San Diego Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Interstitial cystitis/bladder pain syndrome (IC/BPS) is an immense burden to both patients and the American healthcare system; it is notoriously difficult to diagnose. Prevalence estimates vary widely (150-fold range in women and >500-fold range in men). Objectives: We aimed to create accurate national IC/BPS prevalence estimates by employing a novel methodology combining a national population-based dataset with individual chart abstraction. Study design: In this epidemiological survey, all living patients, with ≥2 clinic visits from 2016 to 2018 in the Veterans Health Administration, with an ICD-9/10 code for IC/BPS ( Results: Of the 5,203,529 patients identified, IC/BPS was confirmed in 541 of 1,647 sampled charts with an IC/BPS ICD code, 10 of 382 charts with an ICD-like code, and 3 of 916 controls. After age- and gender-matching to the general US population, this translated to national prevalence estimates of 0.87% (95% CI: 0.32, 1.42), with female and male prevalence of 1.08% (95% CI: 0.03, 2.13) and 0.66% (95% CI: 0.44, 0.87), respectively. Conclusions: We estimate the prevalence of IC/BPS to be 0.87%, which is lower than prior estimates based on survey data, but higher than prior estimates based on administrative data. These potentially represent the most accurate estimates to date, given the broader and more heterogeneous population studied and our novel methodology of combining in-depth chart abstraction with administrative data.

Indexed as

bladder pain syndromeepidemiologyIC/BPSinterstitial cystitisprevalencesex/gender

Identifiers

PMID36093391
PMCPMC9448885
OpenAlexW4292878185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.