Evidence map›Paper›PMID 36093299›Full record

ArticleEuropean journal of case reports in internal medicine2022

A Biphasic COVID-19 Clinical Course in Anti-CD20 Treated Patients: Case Series and Review of the Literature.

Noa Bigman-Peer, Eyal Peer, Barak Pertzov, Mordechai Kramer, Gad Segal, Noa Eliakim-Raz

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Noa Bigman-PeerDepartment of Internal Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Eyal Peer *Oncology Institute, Sheba Medical Center, Ramat Gan, Israel.
Barak PertzovPulmonary Division, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Mordechai KramerPulmonary Division, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Gad SegalSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Noa Eliakim-RazDepartment of Internal Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Rabin Medical Center · ILSheba Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe four cases of COVID-19 infection during the Omicron wave, in patients treated with anti-CD20 monoclonal antibodies. All cases follow a similar biphasic clinical course consisting of respiratory deterioration, which occurred a few weeks after convalescence from initial mild to asymptomatic infection. Possible explanations are discussed. LEARNING POINTS: Four cases of COVID-19 infection in anti-CD20 treated patients are described.These cases display a unique biphasic course that was previously undescribed: respiratory deterioration weeks after convalescence.Awareness of such a course and rapid utilisation of bronchoalveolar lavage will lead to quicker diagnosis and more timely, appropriate treatment.

Indexed as

anti-CD20COVID-19obinutuzumabOmicronrituximab

Identifiers

PMID36093299
PMCPMC9451519
OpenAlexW4293728038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.