Evidence map›Paper›PMID 36093296›Full record

ArticleOncotarget2022

Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors.

Andliena Tahiri, Katarina Puco, Faris Naji, Vessela N Kristensen, Glenny Cecilie Alfsen, Lorant Farkas, Frode S Nilsen, Stig Müller, Jan Oldenburg, Jürgen Geisler

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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  3. Extracellular vesicles: key mediators inFrontiers in veterinary science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Andliena TahiriInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Katarina PucoDepartment of Oncology, Akershus University Hospital, Lørenskog, Norway.
Faris NajiPamgene International BV, 's-Hertogenbosch, The Netherlands.
Vessela N KristensenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Glenny Cecilie AlfsenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Lorant FarkasInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Frode S NilsenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Stig MüllerInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Jan OldenburgInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Jürgen GeislerInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Akershus University Hospital · NOUniversity of Oslo · NOOslo University Hospital · NOPamGene (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinase activity is frequently altered in renal cell carcinoma (RCC), and tyrosine kinase inhibitors (TKIs) are part of the standard treatment strategy in patients with metastatic disease. However, there are still no established biomarkers to predict clinical benefits of a specific TKI. Here, we performed protein tyrosine kinase (PTK) profiling using PamChip

Indexed as

Carcinoma, Renal CellProtein Kinase InhibitorsProtein-Tyrosine KinasesAnilidesHumansIndazolesKidney NeoplasmsNerve Growth FactorsPhenylurea CompoundsPhosphatidylinositol 3-KinasesPhosphatidylinositolsPyridinesPyrimidinesQuinolinessrc-Family KinasesSulfonamidesAnilidescabozantinibIndazolesNerve Growth FactorspazopanibPhenylurea CompoundsPhosphatidylinositol 3-KinasesPhosphatidylinositolsProtein Kinase InhibitorsProtein-Tyrosine KinasesPyridinesPyrimidinesQuinolinessrc-Family KinasesSulfonamidesSunitinibtivozanibkidney cancerkinase activityrenal cell carcinomatyrosine kinasetyrosine kinase inhibitors

Identifiers

PMID36093296
PMCPMC9450987
OpenAlexW4289837131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.