Evidence map›Paper›PMID 36093187›Full record

ArticleFrontiers in cellular and infection microbiology2022

Cephalosporins-induced intestinal dysbiosis exacerbated pulmonary endothelial barrier disruption in streptococcus pneumoniae-infected mice.

Jia-Feng Wang, Chang-Yi Shi, Hua-Zhong Ying

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jia-Feng WangKey Laboratory of Experimental Animal and Safety Evaluation, Hangzhou Medical College, Hangzhou, China.
Chang-Yi ShiKey Laboratory of Experimental Animal and Safety Evaluation, Hangzhou Medical College, Hangzhou, China.
Hua-Zhong YingKey Laboratory of Experimental Animal and Safety Evaluation, Hangzhou Medical College, Hangzhou, China.
Hangzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic abuse is growing more severe in clinic, and even short-term antibiotic treatment can cause long-term gut dysbiosis, which may promote the development and aggravation of diseases. Cephalosporins as the broad-spectrum antibiotics are widely used for prevention and treatment of community-acquired respiratory tract infection in children. However, their potential consequences in health and disease have not been fully elaborated. In this study, the effects of cefaclor, cefdinir and cefixime on intestinal microbiota and lung injury were investigated in

Indexed as

CephalosporinsDysbiosisAnimalsAnti-Bacterial AgentsCefaclorCefdinirCefiximeInflammationMiceStreptococcus pneumoniaeAnti-Bacterial AgentsCefaclorCefdinirCefiximeCephalosporinsbutyratecommunity-acquired infectionendothelial barrierendotoxinprobiotic

Identifiers

PMID36093187
PMCPMC9449322
OpenAlexW4293212769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.