ReviewFrontiers in endocrinology2022
Establishment and identification of an animal model of long-term exercise-induced fatigue.
Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of exercise intervention on children and adolescents with depression: a systematic review and meta-analysis of randomized controlled trial.Frontiers in psychiatry · 2025Pooled it
- Mediating pathways of physical capabilities: linking perceived physical fatigability to motoric cognitive risk syndrome in community older adults.BMC geriatrics · 2026Article
- Ganoderic Acid A Enhances Glycometabolism in Mouse Gastrocnemius Muscle During Exercise-Induced Fatigue via AMPK/PGC-1α Pathway Activation.Food science & nutrition · 2026Article
- Review
- Study on anti-fatigue effect and mechanism of iron source combined with Angelica sinensis and Agrimonia pilosa on pigeons under exercise stress.Poultry science · 2025Article
- Review
- Protective Effects of Ganoderma Triterpenoids Supplementation Against Myocardial Injury in Exhaustion Exercise Mice via Regulation of the Keap1/Nrf2/HO-1 Pathway.Food science & nutrition · 2025Article
- CaBiomolecules · 2025Review
- Whey Protein Mitigates Oxidative Stress Injury and Improves Protein Synthesis in Mouse Skeletal Muscle by Regulating the SIRT1/Nrf2/HO-1 Axis and AMPK/TSC2/mTOR/4EBP1 Pathway.Journal of food science · 2025Article
- Overlaps of Skeletal Muscle Fatigue and Skeletal Muscle Damage: The Muscle Injury Continuum.Sports medicine - open · 2025Review
- Potential mechanisms underlying pathological fatigue-induced cardiac dysfunction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Article
- Gallic acid alleviates exercise-induced muscle damage by inhibiting mitochondrial oxidative stress and ferroptosis.Journal of translational medicine · 2025Article
- Animal models of tendon calcification: Past, present, and future.Animal models and experimental medicine · 2024Review
- Revealing the Complexity of Fatigue: A Review of the Persistent Challenges and Promises of Artificial Intelligence.Brain sciences · 2024Review
- Ninjin'yoeito reduces fatigue-like conditions by alleviating inflammation of the brain and skeletal muscles in aging mice.PloS one · 2024Article
- Swimming behavior indicates stress and adaptations to exercise.Frontiers in physiology · 2024Article
- Comparison of alterations in local field potentials and neuronal firing in mouse M1 and CA1 associated with central fatigue induced by high-intensity interval training and moderate-intensity continuous training.Frontiers in neuroscience · 2024Article
- Aqueous Extract ofNutrients · 2023Article
- Dietary Polysaccharides Exert Anti-Fatigue Functions via the Gut-Muscle Axis: Advances and Prospectives.Foods (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In competitive sports, the training load is close to the human physiological limit, which will inevitably lead to exercise-induced fatigue. If fatigue cannot be recovered in time, it will eventually lead to excessive training and affect sport performance. Therefore, fatigue has become an important part of the physical function assessment for athletes. This paper will review animal models of long-term exercise-induced fatigue, modeling schemes of mice under treadmill and swimming training, phenotypes of long-term exercise-induced fatigue (e.g., nervous system damage, myocardial cell damage, bone mineral density changes, and skeletal muscle damage), and fatigue indicators. The relationship between physiological indicators and biomarkers and long-term exercise-induced fatigue is analyzed to promote exercise-induced fatigue monitoring. This paper attempts to provide a reference for the selection of animal models of long-term exercise-induced fatigue and provide a new theoretical basis for medical supervision and recovery of exercise-induced fatigue.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.