Evidence map›Paper›PMID 36093065›Full record

ArticleiScience2022

Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis.

Yu Yu, Wenjing Yang, Tianming Yu, Xiaojing Zhao, Zheng Zhou, Yanbo Yu, Lifeng Xiong, Hui Yang, Anthony J Bilotta, Suxia Yao and 6 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  5. The Combination ofJournal of microbiology and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Yu YuDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Wenjing YangDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Tianming YuDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Xiaojing ZhaoDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Zheng ZhouDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Yanbo YuDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Lifeng XiongDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
Hui YangDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Anthony J BilottaDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Suxia YaoDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
George GolovkoDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Agustin PlasenciaAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard University Medical School, Boston, MA 02115, USA.
Francisco J QuintanaAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard University Medical School, Boston, MA 02115, USA.
Liang ZhouDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
Yanqing LiDepartment of Gastroenterology, Qilu Hospital, Shandong University, Jinan 250012, P.R. China.
Yingzi CongDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
The University of Texas Medical Branch at Galveston · USQilu Hospital of Shandong University · CNBrigham and Women's Hospital · USUniversity of Florida · US

Funding

STING signaling in T cells regulation of intestinal homeostasis and inflammatorybowel diseasesR01DK124132 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CONG, YINGZI · 2020 to 2024
$2.5M
Th17-IgA Axis in Regulation of Intestinal InflammationR01DK105585 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CONG, YINGZI · 2016 to 2020
$1.8M
GPR120 regulation of inflammatory bowel diseaseR01DK125011 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CONG, YINGZI · 2020 to 2022
$1.5M
Microbiota metabolites, GPR, and inflammatory bowel diseasesR01DK112436 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CONG, YINGZI · 2017 to 2020
$1.4M
GPR120 regulation of intestinal IgA responses and gut IgA-coated bacteriaR21AI150210 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SUN, JIAREN · 2020 to 2021
$435k
NIAID NIH HHS R21 AI150210NIDDK NIH HHS R01 DK105585NIDDK NIH HHS R01 DK112436NIDDK NIH HHS R01 DK124132NIDDK NIH HHS R01 DK125011
6 · The paper itself

Abstract

Glucose, the critical energy source in the human body, is considered a potential risk factor in various autoimmune diseases when consumed in high amounts. However, the roles of glucose at moderate doses in the regulation of autoimmune inflammatory diseases and CD4

Indexed as

Biological sciencesCell biologyComponents of the immune systemImmunology

Identifiers

PMID36093065
PMCPMC9460814
OpenAlexW4292848234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.