Evidence map›Paper›PMID 36093000›Full record

ArticleChemical science2022

Tuning through-space interactions

Isra S Hassan, Jack T Fuller, Vanessa N Dippon, Angeline N Ta, Michael W Danneman, Brian R McNaughton, Anastassia N Alexandrova, Tomislav Rovis

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Isra S HassanDepartment of Chemistry, Columbia University New York NY 10027 USA tr2504@columbia.edu.
Jack T FullerDepartment of Chemistry & Biochemistry, University of California Los Angeles Los Angeles CA 90095 USA ana@chem.ucla.edu.
Vanessa N DipponDepartment of Chemistry, Columbia University New York NY 10027 USA tr2504@columbia.edu.
Angeline N TaDepartment of Chemistry, Colorado State University Fort Collins CO 80523 USA bmcnaughton@desu.edu.
Michael W DannemanDepartment of Chemistry, Columbia University New York NY 10027 USA tr2504@columbia.edu.
Brian R McNaughtonDepartment of Chemistry, Colorado State University Fort Collins CO 80523 USA bmcnaughton@desu.edu.
Anastassia N AlexandrovaDepartment of Chemistry & Biochemistry, University of California Los Angeles Los Angeles CA 90095 USA ana@chem.ucla.edu.ORCID https://orcid.org/0000-0002-3003-1911
Tomislav RovisDepartment of Chemistry, Columbia University New York NY 10027 USA tr2504@columbia.edu.ORCID https://orcid.org/0000-0001-6287-8669
Columbia University · USColorado State University · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report computationally-guided protein engineering of monomeric streptavidin Rh(iii) artificial metalloenzyme to enhance catalysis of the enantioselective coupling of acrylamide hydroxamate esters and styrenes. Increased TON correlates with calculated distances between the Rh(iii) metal and surrounding residues, underscoring an artificial metalloenzyme's propensity for additional control in metal-catalyzed transformations by through-space interactions.

Identifiers

PMID36093000
PMCPMC9384688
OpenAlexW4288776218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.