Evidence map›Paper›PMID 36092756›Full record

ArticleClinical and experimental hepatology2022

The predictive value of MELDNa (model for end-stage liver disease-sodium) and mean platelet volume/platelet count for patients' 30-day mortality after liver transplantation.

Vecihe Bayrak, Mehmet Çağatay Gürkök, Ferhan Demirer Aydemir, Bişar Ergün, Tufan Egeli, Nurcan Şentürk Durukan, Tarkan Ünek, Necati Gökmen

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Article in Clinical and experimental hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Vecihe BayrakDepartment of Internal Medicine, Adult Intensive Care Unit, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Mehmet Çağatay GürkökDepartment of General and Digestive Surgery, Adult Intensive Care Unit, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Ferhan Demirer AydemirDepartment of Internal Medicine, Adult Intensive Care Unit, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Bişar ErgünDepartment of Internal Medicine, Adult Intensive Care Unit, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Tufan EgeliDepartment of General Surgery, Hepatopancreaticobiliary Surgery and Liver Transplantation Unit, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Nurcan Şentürk DurukanDepartment of Public Health, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Tarkan ÜnekDepartment of General Surgery, Hepatopancreaticobiliary Surgery and Liver Transplantation Unit, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Necati GökmenDepartment of Anesthesia and Reanimation, Adult Intensive Care Unit,Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim of the study: To investigate the disease-specific score and improve the existing scores to better determine the prognosis of patients after liver transplantation (LT). For this purpose, we evaluated the relationship of prognostic scores with 30-day mortality after LT. In addition, we planned to investigate whether the mean platelet volume/platelet count (MPR) would contribute to score improvement. Material and methods: A total of 178 adult patients admitted to the intensive care unit after LT in our hospital between 2011 and 2019 were retrospectively analyzed. Model for end-stage liver disease-sodium (MELDNa), Child-Turcotte-Pugh (CTP) score, and MPR values were compared in patients with and without 30-day mortality who underwent LT. Logistic regression analysis was performed to determine the predictive factors for mortality. A model was created with multivariate analysis. Results: Our study included 135 (75.8%) male and 43 (24.2%) female patients. There was a significant difference in the postLT-MELDNa score in the evaluation between those with and without mortality ( Conclusions: In our study, postLT-MELDNa predicted 30-day mortality and was much more effective in predicting mortality when evaluated with age. The MELDNa score, which is currently used in the prognosis of candidates awaiting LT, may be useful for the prognosis of patients after LT in intensive care units.

Indexed as

Child-Turcotte-Pugh scoreICU mortalityICU scoresliver transplant patientMPV/PLT

Identifiers

PMID36092756
PMCPMC9442658

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.