Evidence map›Paper›PMID 36092727›Full record

ReviewFrontiers in cell and developmental biology2022

An evolutionary and physiological perspective on cell-substrate adhesion machinery for cell migration.

Julio C Fierro Morales, Qian Xue, Minna Roh-Johnson

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Deciphering the impact ofGenes & diseases · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Reduced cell-substrate adhesion formation promotes cell migration inbioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Random walk and cell morphology dynamics inFrontiers in cell and developmental biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julio C Fierro MoralesDepartment of Biochemistry, University of Utah, Salt Lake City, UT, United States.
Qian XueDepartment of Biochemistry, University of Utah, Salt Lake City, UT, United States.
Minna Roh-JohnsonDepartment of Biochemistry, University of Utah, Salt Lake City, UT, United States.

Funding

Cell Biological Mechanisms of Melanoma Cell Motility In VivoR00CA190836 · NCI · UNIVERSITY OF UTAH · PI ROH, MINNA · 2018 to 2020
$954k
NCI NIH HHS R00 CA190836
6 · The paper itself

Abstract

Cell-substrate adhesion is a critical aspect of many forms of cell migration. Cell adhesion to an extracellular matrix (ECM) generates traction forces necessary for efficient migration. One of the most well-studied structures cells use to adhere to the ECM is focal adhesions, which are composed of a multilayered protein complex physically linking the ECM to the intracellular actin cytoskeleton. Much of our understanding of focal adhesions, however, is primarily derived from

Indexed as

cell migrationcell-substrate adhesionevolutionfocal adhesionin vivo environment

Identifiers

PMID36092727
PMCPMC9453864

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.