Evidence map›Paper›PMID 36092713›Full record

ArticleFrontiers in cell and developmental biology2022

Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects.

Shaili D Patel, Deepti Anand, Hozumi Motohashi, Fumiki Katsuoka, Masayuki Yamamoto, Salil A Lachke

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shaili D PatelDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Deepti AnandDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Hozumi MotohashiDepartment of Gene Expression Regulation, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan.
Fumiki KatsuokaDepartment of Integrative Genomics, Tohoku University Tohoku Medical Megabank Organization, Sendai, Japan.
Masayuki YamamotoDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Salil A LachkeDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Tohoku University · JPUniversity of Delaware · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Shawn W Polson · 2012 to 2026
$67.2M
POST TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN THE LENS (LENS GENE EXPRESSIONR01EY021505 · NEI · WASHINGTON UNIVERSITY · PI LACHKE, SALIL · 2011 to 2024
$5.3M
RNA-binding proteins in early eye development.R01EY029770 · NEI · UNIVERSITY OF DELAWARE · PI LACHKE, SALIL · 2019 to 2023
$1.7M
Acquisition of a Zeiss LSM710 Confocal MicroscopeS10RR027273 · NCRR · UNIVERSITY OF DELAWARE · PI DUNCAN, MELINDA K · 2010 to 2010
$494k
NCRR NIH HHS S10 RR027273NEI NIH HHS R01 EY021505NEI NIH HHS R01 EY029770NIGMS NIH HHS P20 GM103446
6 · The paper itself

Abstract

Deficiency of the small Maf proteins Mafg and Mafk cause multiple defects, namely, progressive neuronal degeneration, cataract, thrombocytopenia and mid-gestational/perinatal lethality. Previous data shows

Indexed as

bZIP transcription factorsdevelopmenteph signalingepitheliumlensMAFGMAFKtranscription

Identifiers

PMID36092713
PMCPMC9459095
OpenAlexW4293199968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.