Evidence map›Paper›PMID 36092469›Full record

ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2022

Nitazoxanide, Ivermectin, and Artemether effects against cryptosporidiosis in diabetic mice: parasitological, histopathological, and chemical studies.

Ayman M El-Ashkar, Soheir Mahmoud, Hoda Sabry, Nevine Guirguis, Wafaa El Komi, Eman Ali, Tarek Abu Shousha, Hagar F Abdelmksoud

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Efficacy of nitazoxanide, ivermectin and albendazole in treatment of cryptosporidiosis in immunosuppressed mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  2. Review
  3. Evaluation of the therapeutic efficacy of some essential oils in experimentally immunosuppressed mice infected withJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ayman M El-AshkarDepartment of Medical Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID 0000-0003-4815-8731
Soheir MahmoudDepartment of Medical Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
Hoda SabryDepartment of Medical Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
Nevine GuirguisDepartment of Medical Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
Wafaa El KomiDepartment of Medical Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
Eman AliDepartment of Medical Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
Tarek Abu ShoushaDepartment of Pathology, Theodor Bilharz Research Institute, Giza, Egypt.
Hagar F AbdelmksoudDepartment of Medical Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
Theodor Bilharz Research Institute · EGAin Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cryptosporidiosis is one of the most significant causes of water borne epidemics of diarrhea worldwide. It is extremely important in immunocompromised hosts and malnourished children as it could cause severe life-threatening diarrhea. Despite the global burden of the disease, there are only few available therapies against cryptosporidiosis. Diabetes mellitus is a common metabolic disorder that impair both the innate and adaptive immune responses of the patient. This study aimed to test the effect of Nitazoxanide, Ivermectin, and Artemether against cryptosporidiosis in diabetic mice. Sixty white albino mice were categorized into 6 groups; 10 mice each: Graphical abstract:

Indexed as

ArtemetherCryptosporidiumDiabetes mellitusIvermectinNitazoxanide

Identifiers

PMID36092469
PMCPMC9451122
OpenAlexW4294898120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.