Evidence map›Paper›PMID 36092381›Full record

ArticleAvicenna journal of medicine2022

Acute Liver Injury due to Glecaprevir/Pibrentasvir in a Patient with Chronic Hepatitis C Virus Infection without Cirrhosis.

Ayushi Jain, Khalid Mumtaz

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Avicenna journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ayushi JainDepartment of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States.ORCID 0000-0002-1037-3500
Khalid MumtazDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States.
The Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We reported a rare case of acute liver injury in a patient with chronic hepatitis C virus infection without cirrhosis 4 weeks after initiation of glecaprevir/pibrentasvir. After prompt cessation of antiviral therapy, liver enzymes rapidly improved toward baseline. This case reflects the need to remain vigilant for the development of acute liver injury after initiation of glecaprevir/pibrentasvir even without a diagnosis of cirrhosis.

Indexed as

acute liver injurydrug induced liver injuryglecaprevir/pibrentasvirhepatitis C

Identifiers

PMID36092381
PMCPMC9458352
OpenAlexW4283802994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.