Evidence map›Paper›PMID 36092302›Full record

ArticleBrain communications2022

Impairment in social interaction and hippocampal long-term potentiation at perforant pathway-dentate gyrus synapses in a prenatal valproic acid-induced rat model of autism.

Reihaneh Mohammadkhani, Reza Ghahremani, Iraj Salehi, Samaneh Safari, Seyed Asaad Karimi, Mohammad Zarei

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Reihaneh MohammadkhaniNeurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan 65178/518, Iran.
Reza GhahremaniNeurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan 65178/518, Iran.
Iraj SalehiNeurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan 65178/518, Iran.
Samaneh SafariNeurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan 65178/518, Iran.
Seyed Asaad KarimiNeurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan 65178/518, Iran.ORCID https://orcid.org/0000-0002-8663-6485
Mohammad ZareiNeurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan 65178/518, Iran.
Hamedan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well established that prenatal valproic acid exposure in rats leads to autism-like behaviours and social deficits. Long-term potentiation changes in the brain have been proposed as a potential mechanism in the development of autistic behaviour. However, there are controversies regarding the effect of

Indexed as

autism spectrum disorderhippocampuslong-term potentiationsocial interactionvalproic acid

Identifiers

PMID36092302
PMCPMC9453432
OpenAlexW4294607209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.