Evidence map›Paper›PMID 36092266›Full record

ArticleSkin health and disease2022

Microdermabrasion facilitates direct current stimulation by lowering skin resistance.

P Y Chhatbar, S Liu, V Ramakrishnan, M S George, S A Kautz, W Feng

Open access · goldAbstract read
In one paragraph

Article in Skin health and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Psychodermatology special edition.Skin health and disease · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

P Y ChhatbarDepartment of Neurology Duke University School of Medicine Durham North Carolina USA.ORCID https://orcid.org/0000-0001-6436-8427
S LiuDepartment of Neurology Tiantan Hospital Capital Medical University Beijing China.
V RamakrishnanDepartment of Public Health Sciences Medical University of South Carolina Charleston South Carolina USA.
M S GeorgePsychiatry and Behavioral Science Brain Stimulation Laboratory College of Medicine Charleston South Carolina USA.
S A KautzDepartment of Health Science & Research College of Health Professions Medical University of South Carolina Charleston South Carolina USA.
W FengDepartment of Neurology Duke University School of Medicine Durham North Carolina USA.
Medical University of South Carolina · USCapital Medical University · CNDuke University · US

Funding

Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
Techniques DevelopmentP2CHD086844 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2015 to 2024
$12.7M
South Carolina Collaborative Alliance for Stroke Trials (SC-CoAST)U10NS086490 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JAUCH, EDWARD C · 2013 to 2017
$1.6M
Realistic Measurements of tDCS-Modulated Activity and Electric Fields in the Human Brain In VivoR03HD094614 · NICHD · DUKE UNIVERSITY · PI CHHATBAR, PRATIK YASHVANT · 2019 to 2020
$319k
NICHD NIH HHS P2C HD086844NICHD NIH HHS R03 HD094614NIGMS NIH HHS P20 GM109040NINDS NIH HHS U10 NS086490
6 · The paper itself

Abstract

Background: Transcranial direct current stimulation (tDCS) is reported to induce irritating skin sensations and occasional skin injuries, which limits the applied tDCS dose. Additionally, tDCS hardware safety profile prevents high current delivery when skin resistance is high. Objective: To test if decreasing skin resistance can enable high-dose tDCS delivery without increasing tDCS-related skin sensations or device hardware limits. Methods: We compared the effect of microdermabrasion and sonication on 2 mA direct current stimulation (DCS) through forearm skin for 2-3 min on 20 subjects. We also surveyed the subjects using a questionnaire throughout the procedure. We used a linear mixed-effects model for repeated-measures and multiple logistic regression, with adjustments for age, race, gender and visit. Results: Microdermabrasion, with/out sonication, led to significant decrease in skin resistance (1.6 ± 0.1 kΩ or ∼32% decrease, Conclusions: Microdermabrasion (with/out sonication) resulted in reduced skin resistance without increase in perceived skin sensations with DCS. Higher current can be delivered with microdermabrasion-pre-treated skin without changing the device hardware while reducing, otherwise higher voltage required to deliver the same amount of current.

Identifiers

PMID36092266
PMCPMC9435456
OpenAlexW3211584550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.