ReviewFrontiers in oral health2022
Understanding dental caries as a non-communicable and behavioral disease: Management implications.
Review in Frontiers in oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- The role of probiotics in preventing dental caries: a systematic review of clinical evidence.Frontiers in oral health · 2025Pooled it
- Trial
- [Efficacy and cost analysis of two fluoride varnishes in community-based interventions for early childhood caries].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Trial
- Parental oral health knowledge and sociodemographic influences in children aged 2-12 years: a cross-sectional study in Valencia, Spain.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Ultrasensitive multiplex salivary cytokine profiling reveals distinct immune signatures in dental caries.BDJ open · 2026Article
- Integrated Dentist-Nurse Collaborative Care Model for Caries Management in China.Dentistry journal · 2026Review
- Changes in Oral Health-Related Quality of Life Following Restorative Dental Treatment of Untreated Dental Caries: A Prospective Study in the Saudi Population.Oral health & preventive dentistry · 2026Article
- Sodium Fluoride Varnish, Silver Diamine Fluoride, and Herbal ( Solanum trilobatum [fruit] and amla) Silver Nanoparticle Varnish Antibacterial Activity against Streptococcus mutans.Annals of African medicine · 2026Article
- From Caries to Periodontal Breakdown: A Biological and Clinical Continuum Linking Cariology, Operative Dentistry, Endodontics, and Periodontology.Dentistry journal · 2026Review
- In Vitro Antibacterial and Antibiofilm Effects of Antiseptics and Mouthwashes onPathogens (Basel, Switzerland) · 2026Article
- Streptococcus dentisani and Streptococcus mutans in dental biofilm of preschoolers with and without early childhood caries: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Evaluation of the Remineralisation and Antibacterial Properties of Propolis, Chitosan, and Theobromine.Oral health & preventive dentistry · 2026Article
- Demographic, Geographic, and Temporal Patterns of Adult Dental Emergency Presentations in Arad County, Western Romania.Healthcare (Basel, Switzerland) · 2026Article
- Fluoride release and mechanical properties of S-PRG fillers in dental materials: a systematic review and meta-analysis.BDJ open · 2026Review
- Influence of Rural and Urban Environments on Lifestyle, Dietary Patterns, and Oral Health Among Adolescents in Mallorca: A Cross-Sectional Study.Children (Basel, Switzerland) · 2026Article
- Article
- Can the Severity of Dental Caries Predict Hypertension in Adult Patients?Health science reports · 2026Article
- Article
- Efficacy of topical strategies to prevent the onset of root caries lesions: an in vitro study.Odontology · 2026Article
- Living alone and oral health disparities in Chinese older adults: a national cross-sectional study.BMC public health · 2026Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
New paradigms in caries conceptualization have emerged during the last decades, leading to intense debate and discussion on how to approach the disease, both from a preventive and a therapeutic perspective. Among many new ideas, research discoveries and technologies, one major concept can be highlighted that created a deep frontier between the old and the new paradigm in caries conceptualization; the non-communicable nature of the disease, firmly associated with behaviors and lifestyles. This article synthetizes the conceptual construction of dental caries as a non-communicable disease (NCD) based on the current evidence and discusses the appropriate management of the disease in this context. Dental caries has shifted from being considered transmissible and infectious to an ecological and non-communicable disease. Environmental factors such as frequent sugars intake, disrupt the symbiosis of the dental biofilm leading to a dysbiosis, which favors caries lesion initiation and progression. As an NCD, dental caries shares characteristics with other NCDs such as cardiovascular and chronic respiratory diseases, cancer and diabetes, including long duration and slow progression, not being transmissible from person-to-person, being strongly related to modifiable behavioral risk factors, and affecting preferentially disadvantaged populations with a strong inequality gradient. Given the high prevalence of dental caries, and its consequences on people's health and quality of life, a recognizable conceptual view of caries as a NCD is required to target an effective management. Current understanding of dental caries supports prevention through acting on the modifiable risk factors (behaviors) and involves management based on an interdisciplinary approach. Communicating these modern concepts among researchers, clinicians and policymakers is needed to decrease the global high burden of the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.