ArticlePeerJ. Computer science2022
Gene Ontology Capsule GAN: an improved architecture for protein function prediction.
Article in PeerJ. Computer science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- An informatic workflow for the enhanced annotation of excretory/secretory proteins ofComputational and structural biotechnology journal · 2023Article
- Gene Ontology Capsule GAN: an improved architecture for protein function prediction.PeerJ. Computer science · 2022Article
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Authors and funding
4 authors.
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Abstract
Proteins are the core of all functions pertaining to living things. They consist of an extended amino acid chain folding into a three-dimensional shape that dictates their behavior. Currently, convolutional neural networks (CNNs) have been pivotal in predicting protein functions based on protein sequences. While it is a technology crucial to the niche, the computation cost and translational invariance associated with CNN make it impossible to detect spatial hierarchies between complex and simpler objects. Therefore, this research utilizes capsule networks to capture spatial information as opposed to CNNs. Since capsule networks focus on hierarchical links, they have a lot of potential for solving structural biology challenges. In comparison to the standard CNNs, our results exhibit an improvement in accuracy. Gene Ontology Capsule GAN (GOCAPGAN) achieved an F1 score of 82.6%, a precision score of 90.4% and recall score of 76.1%.
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Registered trials
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