Evidence map›Paper›PMID 36091909›Full record

ArticleChemical science2022

Non-ergodicity of a globular protein extending beyond its functional timescale.

Jun Li, JingFei Xie, Aljaž Godec, Keith R Weninger, Cong Liu, Jeremy C Smith, Liang Hong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Activation dynamics of a water-soluble human mu-opioid receptor.The Journal of biological chemistry · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun LiSchool of Physics and Astronomy, Shanghai Jiao Tong University Shanghai 200240 China.ORCID https://orcid.org/0000-0001-9241-9260
JingFei XieInterdisciplinary Research Center on Biology and Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Shanghai 201203 China.
Aljaž GodecMathematical BioPhysics Group, Max Planck Institute for Biophysical Chemistry Göttingen 37077 Germany.
Keith R WeningerDepartment of Physics, North Carolina State University Raleigh NC 27695 USA.
Cong LiuInterdisciplinary Research Center on Biology and Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Shanghai 201203 China.ORCID https://orcid.org/0000-0003-3425-6672
Jeremy C SmithUT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory Oak Ridge Tennessee 37831 USA.
Liang HongSchool of Physics and Astronomy, Shanghai Jiao Tong University Shanghai 200240 China.ORCID https://orcid.org/0000-0003-0107-336X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Internal motions of folded proteins have been assumed to be ergodic,

Identifiers

PMID36091909
PMCPMC9400594

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.